Electrospinning and Structure of Bicomponent Polycaprolactone/Gelatin Nanofibers Obtained Using Alternative Solvent System

被引：60

作者：

Denis, Piotr ^{[1
]}

Dulnik, Judyta ^{[1
]}

Sajkiewicz, Pawel ^{[1
]}

机构：

[1] Polish Acad Sci, Inst Fundamental Technol Res, PL-02106 Warsaw, Poland

来源：

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS | 2015年 / 64卷 / 07期

关键词：

Alternative solvents; electrospinning; gelatin; nanofibers; polycaprolactone; structure; COLLAGEN NANOFIBERS; MECHANICAL-PROPERTIES; GELATIN FIBERS; SCAFFOLDS; FABRICATION; MORPHOLOGY; BLENDS; FILMS; ACID;

D O I：

10.1080/00914037.2014.945208

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

082905 [生物质能源与材料]; 100103 [病原生物学];

摘要：

Bicomponent polycaprolactone/gelatin (PCL/Gt) nanofibers were successfully formed for the first time by electrospinning using a novel polymer-solvent system with solvents being alternative to the commonly used toxic solvents like fluorinated alcohols. The mixture of acetic acid (AA) with formic acid (FA; 90: 10) was applied. Stable electrospinning was possible despite the fact the mixture of PCL and gelatin in AA/FA solvent showed emulsive structure. From the practical perspective, there is no doubt that it is possible to obtain PCL/Gt fibers using AA/FA mixture with morphology similar to that for fibers spun from hexafluoroisopropanol (HFIP) solutions. [GRAPHICS] .

引用

页码：354 / 364

页数：11

共 33 条

[1]

Relationship between triple-helix content and mechanical properties of gelatin films [J].

Bigi, A ;

Panzavolta, S ;

Rubini, K .

BIOMATERIALS, 2004, 25 (25) :5675-5680

[2]

Borges J. P., 2010, TISS ENG REG MED INT

[3]

Electrospinning of type I collagen and PCL nanofibers using acetic acid [J].

Chakrapani, V. Yogeshwar ;

Gnanamani, A. ;

Giridev, V. R. ;

Madhusoothanan, M. ;

Sekaran, G. .

JOURNAL OF APPLIED POLYMER SCIENCE, 2012, 125 (04) :3221-3227

[4]

Electrospun gelatin fibers: Effect of solvent system on morphology and fiber diameters [J].

Choktaweesap, Nuanchan ;

Arayanarakul, Kunawan ;

Aht-Ong, Duangdao ;

Meechaisue, Chidchanok ;

Supaphol, Pitt .

POLYMER JOURNAL, 2007, 39 (06) :622-631

[5]

Formation of a molten-globule-like state of myoglobin in aqueous hexafluoroisopropanol [J].

Cort, JR ;

Andersen, NH .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 233 (03) :687-691

[6]

Doillon CJ, 1997, J BIOMED MATER RES, V37, P212

[7]

Formalas A., 1934, US Patent, Patent No. [1975504, US1975504A]

[8]

Thermoresponsive Semicrystalline Poly(ε-caprolactone) Networks: Exploiting Cross-linking with Cinnamoyl Moieties to Design Polymers with Tunable Shape Memory [J].

Garle, Amit ;

Kong, Sany ;

Ojha, Umaprassana ;

Budhlall, Bridgette M. .

ACS APPLIED MATERIALS & INTERFACES, 2012, 4 (02) :645-657

[9]

Fabrication and characterization of PCL/gelatin composite nanofibrous scaffold for tissue engineering applications by electrospinning method [J].

Gautam, Sneh ;

Dinda, Amit Kumar ;

Mishra, Narayan Chandra .

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2013, 33 (03) :1228-1235

[10]

Role of pH on stability and mechanical properties of gelatin films [J].

Gioffre, Michela ;

Torricelli, Paola ;

Panzavolta, Silvia ;

Rubini, Katia ;

Bigi, Adriana .

JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, 2012, 27 (01) :67-77

← 1 2 3 4 →