Periscope, up! Monitoring microbes in the intestine

被引:16
作者
Gewirtz, AT [1 ]
Madara, JL [1 ]
机构
[1] Emory Univ, Dept Pathol, WMB 2315, Atlanta, GA 30322 USA
关键词
D O I
10.1038/86292
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 [免疫学];
摘要
Dendritic cells below the epithelium layer are now reported to send processes in between epithelial cells, while maintaining the integrity of the tight junctions. This mechanism could sample intestinal fluids for pathogens to aid immunologic protection of the host.
引用
收藏
页码:288 / 290
页数:3
相关论文
共 13 条
[1]
Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response [J].
Gewirtz, AT ;
Simon, PO ;
Schmitt, CK ;
Taylor, LJ ;
Hagedorn, CH ;
O'Brien, AD ;
Neish, AS ;
Madara, JL .
JOURNAL OF CLINICAL INVESTIGATION, 2001, 107 (01) :99-109
[2]
Microbial lipopeptides stimulate dendritic cell maturation via toll-like receptor 2 [J].
Hertz, CJ ;
Kiertscher, SM ;
Godowski, PJ ;
Bouis, DA ;
Norgard, MV ;
Roth, MD ;
Modlin, RL .
JOURNAL OF IMMUNOLOGY, 2001, 166 (04) :2444-2450
[3]
Hooper LV, 1998, BIOESSAYS, V20, P336, DOI 10.1002/(SICI)1521-1878(199804)20:4&lt
[4]
336::AID-BIES10&gt
[5]
3.0.CO
[6]
2-3
[7]
[8]
Madara JL, 1997, ALIMENT PHARM THERAP, V11, P57
[9]
SALMONELLA-TYPHIMURIUM ATTACHMENT TO HUMAN INTESTINAL EPITHELIAL MONOLAYERS - TRANSCELLULAR SIGNALING TO SUBEPITHELIAL NEUTROPHILS [J].
MCCORMICK, BA ;
COLGAN, SP ;
DELPARCHER, C ;
MILLER, SI ;
MADARA, JL .
JOURNAL OF CELL BIOLOGY, 1993, 123 (04) :895-907
[10]
Prokaryotic regulation of epithelial responses by inhibition of IκB-α ubiquitination [J].
Neish, AS ;
Gewirtz, AT ;
Zeng, H ;
Young, AN ;
Hobert, ME ;
Karmali, V ;
Rao, AS ;
Madara, JL .
SCIENCE, 2000, 289 (5484) :1560-1563