Gene silencing and DNA methylation processes

被引：123

作者：

Paszkowski, J

Whitham, SA

机构：

[1] Friedrich Miescher Inst, CH-4092 Basel, Switzerland

[2] Iowa State Univ Sci & Technol, Dept Plant Pathol, Ames, IA 50011 USA

来源：

CURRENT OPINION IN PLANT BIOLOGY | 2001年 / 4卷 / 02期

关键词：

D O I：

10.1016/S1369-5266(00)00147-3

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Epigenetic gene silencing results from the inhibition of transcription or from posttranscriptional RNA degradation. DNA methylation is one of the most central and frequently discussed elements of gene silencing in both plants and mammals. Because DNA methylation has not been detected in yeast, Drosophila or Caenorhabditis elegans, the standard genetic workhorses, plants are important models for revealing the role of DNA methylation in the epigenetic regulation of genes in vivo.

引用

页码：123 / 129

页数：7

共 50 条

[1] Disruption of the plant gene MOM releases transcriptional silencing of methylated genes
Amedeo, P
Habu, Y
Afsar, K
Scheid, OM
Paszkowski, J
[J]. NATURE, 2000, 405 (6783) : 203 - 206
[2] Barneche F, 2000, J BIOL CHEM, V275, P27212
[3] Cytosine methylation at CG and CNG sites is not a prerequisite for the initiation of transcriptional gene silencing in plants, but it is required for its maintenance
Diéguez, MJ
Vaucheret, H
Paszkowski, J
Scheid, OM
[J]. MOLECULAR AND GENERAL GENETICS, 1998, 259 (02): : 207 - 215
[4] Arabidopsis mutants impaired in cosuppression
Elmayan, T
Balzergue, S
Béon, F
Bourdon, V
Daubremet, J
Guénet, Y
Mourrain, P
Palauqui, JC
Vernhettes, S
Vialle, T
Wostrikoff, K
Vaucheret, H
[J]. PLANT CELL, 1998, 10 (10) : 1747 - 1757
[5] AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals
Fagard, M
Boutet, S
Morel, JB
Bellini, C
Vaucheret, H
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (21) : 11650 - 11654
[6] (Trans)gene silencing in plants: How many mechanisms?
Fagard, M
Vaucheret, H
[J]. ANNUAL REVIEW OF PLANT PHYSIOLOGY AND PLANT MOLECULAR BIOLOGY, 2000, 51 : 167 - 194
[7] Plant DNA methyltransferases
Finnegan, EJ
Kovac, KA
[J]. PLANT MOLECULAR BIOLOGY, 2000, 43 (2-3) : 189 - 201
[8] Reduced DNA methylation in Arabidopsis thaliana results in abnormal plant development
Finnegan, EJ
Peacock, WJ
Dennis, ES
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (16) : 8449 - 8454
[9] Dosage compensation rox!
Franke, A
Baker, BS
[J]. CURRENT OPINION IN CELL BIOLOGY, 2000, 12 (03) : 351 - 354
[10] The rox1 and rox2 RNAs are essential components of the compensasome, which mediates dosage compensation in Drosophila
Franke, A
Baker, BS
[J]. MOLECULAR CELL, 1999, 4 (01) : 117 - 122

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