Fels-Rand: an Xlisp-Stat program for the comparative analysis of data under phylogenetic uncertainty

被引:4
作者
Blomberg, S [1 ]
机构
[1] Univ Aberdeen, Dept Zool, Aberdeen AB24 2TZ, Scotland
基金
澳大利亚研究理事会;
关键词
D O I
10.1093/bioinformatics/16.11.1010
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Motivation: Currently available programs for the comparative analysis of phylogenetic data do not perform optimally when the phylogeny is not completely specified (i.e. the phylogeny contains polytomies). Recent literature suggests that a better way to analyse the data would be to create random trees from the known phylogeny that are fully-resolved but consistent with the known tree. A computer program is presented, Fels-Rand, that performs such analyses. A randomisation procedure is used to generate trees that are fully resolved but whose structure is consistent with the original tree. Statistics are then calculated on a large number of these randomly-generated trees. Fels-Rand uses the object-oriented features of Xlisp-Stat to manipulate internal tree representations. XIisp-Stat's dynamic graphing features are used to provide heuristic tools to aid in analysis, particularly outlier analysis. The usefulness of Xlisp-Stat as a system for phylogenetic computation is discussed.
引用
收藏
页码:1010 / 1013
页数:4
相关论文
共 23 条