Spectral data of chemical modification products of costunolide

被引：12

作者：

Lu, TS ^{[1
]}

Fischer, NH ^{[1
]}

机构：

[1] LOUISIANA STATE UNIV, DEPT CHEM, BATON ROUGE, LA 70803 USA

来源：

SPECTROSCOPY LETTERS | 1996年 / 29卷 / 03期

关键词：

sesquiterpene lactones; germacranolides; costunolide; epoxidation-cyclization; parthenolide; 1,10-epoxycostunolide; eudesmanolides; reductions; H-1 and C-13 NMR;

D O I：

10.1080/00387019608006662

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Epoxidation of costunolide (1) yielded parthenolide (3), 1,10-epoxycostunolide (4), and the cyclization products of 4, santamarin (5), reynosin (6), magnolialide (7) and a 1,4-epoxyeudesmanolide (8). Reduction of santamarin (5) with sodium borohydride afforded 1 1,13-dihydrosantamarin (9) and an eudesmen-triol (10). Reduction of reynosin (6) provided 11,13-dihydroreynosin (11) and the two eudesman-triols 12 and 13. The structures of the new compounds were elucidated by 1D and 2D H-1 and C-13 NMR spectral methods.

引用

页码：437 / 448

页数：12

共 12 条

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