Antibiotic resistance patterns and plasmid profiles of Salmonella typhimurium isolates in Turkey

被引:9
作者
Otkun, M
Erdem, B [1 ]
Akata, F
Tatman-Otkun, M
Gerceker, D
Yagci, S
Ozkan, E
机构
[1] Ankara Univ, Fac Med, Dept Microbiol & Clin Microbiol, TR-06100 Ankara, Turkey
[2] Trakya Univ, Fac Med, Dept Clin Bacteriol & Infect Dis, Edirine, Turkey
关键词
D O I
10.1007/PL00011253
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
To understand the resistance mechanisms present in 75 isolates of Salmonella typhimurium derived from clinical infections in Turkey, antimicrobial resistance patterns and associated plasmids were investigated. Among the 22 strains that produced extended-spectrum beta -lactamase (ESBL), 20 were resistant to aminoglycosides and 12 to trimethoprim-sulfamethoxazole, Strains that did not produce ESBL did not express aminoglycoside or trimethoprim-sulfamethoxazole resistance, although 27 of them were ampicillin resistant. None of the strains were resistant to imipenem or fluoroquinolones. Nineteen strains producing ESBL carried a plasmid of >100 MDa, Seven ESBL-producing strains conjugally transferred their ESBLs and trimethoprim-sulfamethoxazole resistance. No correlation was found between the resistance patterns and plasmids in non-ESBL-producing strains.
引用
收藏
页码:206 / 209
页数:4
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