Lysosomal proteolysis in skeletal muscle

被引:180
作者
Bechet, D [1 ]
Tassa, A [1 ]
Taillandier, D [1 ]
Cornbaret, L [1 ]
Attaix, D [1 ]
机构
[1] INRA, Human Nutr Res Ctr, Nutr & Prot Metab Unit, F-63122 St Genes Champanelle, France
关键词
skeletal muscle; lysosome; cathepsin; autophagosome; myopathy;
D O I
10.1016/j.biocel.2005.02.029
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Lysosomal proteases are abundantly expressed in fetal muscles, but poorly represented in the adult skeletal muscles. The lysosomal proteolytic system is nonetheless stimulated in adult muscles in a variety of pathological conditions. Furthermore, recent investigations describe autophagosomes in muscle fibers in vitro and in vivo, and report myopathies with excessive autophagy. This review presents our current knowledge about the lysosomal proteolytic system and summarizes the evidences pertaining to the role of lysosomes and autophagosomes in muscle physiology and pathology. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2098 / 2114
页数:17
相关论文
共 124 条
  • [1] Agarraberes FA, 2001, J CELL SCI, V114, P2491
  • [2] PURIFICATION AND TISSUE DISTRIBUTION OF RAT CATHEPSIN-L
    BANDO, Y
    KOMINAMI, E
    KATUNUMA, N
    [J]. JOURNAL OF BIOCHEMISTRY, 1986, 100 (01) : 35 - 42
  • [3] ACTIVATION OF THE ATP-UBIQUITIN-PROTEASOME PATHWAY IN SKELETAL-MUSCLE OF CACHECTIC RATS BEARING A HEPATOMA
    BARACOS, VE
    DEVIVO, C
    HOYLE, DHR
    GOLDBERG, AL
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 1995, 268 (05): : E996 - E1006
  • [4] CIMATEROL REDUCES CATHEPSIN ACTIVITIES BUT HAS NO ANABOLIC EFFECT IN CULTURED MYOTUBES
    BECHET, DM
    LISTRAT, A
    DEVAL, C
    FERRARA, M
    QUIRKE, JF
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1990, 259 (06): : E822 - E827
  • [5] Developmental control of cathepsin B expression in bovine fetal muscles
    Bechet, DM
    Deval, C
    Robelin, J
    Ferrara, MJ
    Obled, A
    [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1996, 334 (02) : 362 - 368
  • [6] BECHET DM, 1991, J BIOL CHEM, V266, P14104
  • [7] EFFECT OF FASTING AND THYROIDECTOMY ON CYSTEINE PROTEINASE ACTIVITIES IN LIVER AND MUSCLE
    BELKHOU, R
    BECHET, D
    CHEREL, Y
    GALLUSER, M
    FERRARA, M
    LEMAHO, Y
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1994, 1199 (02): : 195 - 201
  • [8] BIRD JWC, 1978, PROTEIN TURNOVER LYS, P589
  • [9] Autophagic proteolysis: Control and specificity
    Blommaart, EFC
    Luiken, JJFP
    Meijer, AJ
    [J]. HISTOCHEMICAL JOURNAL, 1997, 29 (05): : 365 - 385
  • [10] Regulation of muscle cathepsin B proteolytic activity in protein-depleted patients with chronic diseases
    Bosutti, A
    Toigo, G
    Ciocchi, B
    Situlin, R
    Guarnieri, G
    Biolo, G
    [J]. CLINICAL NUTRITION, 2002, 21 (05) : 373 - 378