The challenges of assessing acute kidney injury in infants

被引：24

作者：

Filler, Guido M. ^{[1
,2
]}

机构：

[1] Univ Western Ontario, Dept Pediat, Childrens Hosp, London Hlth Sci Ctr,Schulich Sch Med & Dent, London, ON N6A 5W9, Canada

[2] Univ Western Ontario, Dept Pathol & Lab Med, Schulich Sch Med & Dent, London, ON N6A 5W9, Canada

来源：

KIDNEY INTERNATIONAL | 2011年 / 80卷 / 06期

关键词：

GLOMERULAR-FILTRATION-RATE; SERUM CYSTATIN-C; CREATININE; CHILDREN;

D O I：

10.1038/ki.2011.172

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Definitions of pediatric acute kidney injury (AKI) use changes of serum creatinine. There is a paucity of well-designed studies in infants because of creatinine age-dependency. The emerging role of cystatin C as a superior marker of renal dysfunction led to a carefully conducted study on AKI in infants by Zappitelli et al. This Commentary calls for the development of age-independent serum creatinine and estimated glomerular filtration rate z scores. Kidney International (2011) 80, 567-568. doi: 10.1038/ki.2011.172

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收藏

页码：567 / 568

页数：2

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