Functionalization by metalation of the benzene moiety of benzodiazines.: Determination of structures by long-range 1H-15N correlation at natural abundance.: Diazines XXV.

被引：20

作者：

Chapoulaud, VG

Salliot, I

Plé, N

Turck, A

Quéguiner, G

机构：

[1] INSA, IRCOF, Lab Chim Organ Fine & Heterocyclique, UPRES A 6014, F-76131 Mt St Aignan, France

[2] INSA, IRCOF, Ctr Reg & Univ Spect, F-76131 Mt St Aignan, France

来源：

TETRAHEDRON | 1999年 / 55卷 / 17期

关键词：

metalation; benzodiazines; NMR;

D O I：

10.1016/S0040-4020(99)00202-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first lithiation of the benzene moiety of various quinazolinones, quinoxalines, and phthalazines has been performed. The effects of kind and positions of various directing groups towards the regioselectivity of the metalation have been studied. Unambiguous structure determinations of quinoxaline derivatives have been carried out by applying NMR GHMBC H-1-N-15 sequence. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：5389 / 5404

页数：16

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