Vertebrate segmentation: The clock is linked to Notch signalling

被引：44

作者：

Jiang, YJ ^{[1
]}

Smithers, L ^{[1
]}

Lewis, J ^{[1
]}

机构：

[1] Imperial Canc Res Fund, Vertebrate Dev Lab, London WC2A 3PX, England

来源：

CURRENT BIOLOGY | 1998年 / 8卷 / 24期

关键词：

D O I：

10.1016/S0960-9822(07)00547-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The periodic formation of somites during vertebrate segmentation has been suggested to involve a molecular 'segmentation clock'. Recent observations of cyclic Lunatic fringe expression in chick and mouse embryos link the segmentation clock to Delta-Notch signalling.

引用

页码：R868 / R871

页数：4

共 23 条

[1] Requirement of the paraxis gene for somite formation and musculoskeletal patterning
Burgess, R
Rawls, A
Brown, D
Bradley, A
Olson, EN
[J]. NATURE, 1996, 384 (6609) : 570 - 573
[2] CONLON RA, 1995, DEVELOPMENT, V121, P1533
[3] CLOCK AND WAVEFRONT MODEL FOR CONTROL OF NUMBER OF REPEATED STRUCTURES DURING ANIMAL MORPHOGENESIS
COOKE, J
ZEEMAN, EC
[J]. JOURNAL OF THEORETICAL BIOLOGY, 1976, 58 (02) : 455 - 476
[4] Maintenance of somite borders in mice requires the Delta homologue DII1
deAngelis, MH
McIntyre, J
Gossler, A
[J]. NATURE, 1997, 386 (6626) : 717 - 721
[5] Overexpression of a zebrafish homologue of the Drosophila neurogenic gene Delta perturbs differentiation of primary neurons and somite development
Dornseifer, P
Takke, C
CamposOrtega, JA
[J]. MECHANISMS OF DEVELOPMENT, 1997, 63 (02) : 159 - 171
[6] lunatic fringe is an essential mediator of somite segmentation and patterning
Evrard, YA
Lun, Y
Aulehla, A
Gan, L
Johnson, RL
[J]. NATURE, 1998, 394 (6691) : 377 - 381
[7] Waves of mouse Lunatic fringe expression, in four-hour cycles at two-hour intervals, precede somite boundary formation
Forsberg, H
Crozet, F
Brown, NA
[J]. CURRENT BIOLOGY, 1998, 8 (18) : 1027 - 1030
[8] Dorsal-ventral signaling in limb development
Irvine, KD
Vogt, TF
[J]. CURRENT OPINION IN CELL BIOLOGY, 1997, 9 (06) : 867 - 876
[9] Jen WC, 1997, DEVELOPMENT, V124, P1169
[10] KEYNES RJ, 1988, DEVELOPMENT, V103, P413

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