Recent methodology in the phytochemical analysis of ginseng

被引:78
作者
Angelova, Nadezhda [2 ]
Kong, Hong-Wei [1 ,3 ]
Van Der Heijden, Rob [1 ]
Yang, Shih-Ying [2 ]
Choi, Young Hae [2 ]
Kim, Hye Kyong [2 ]
Wang, Mei [4 ,5 ]
Hankemeier, Thomas [1 ]
Van Der Greef, Jan [1 ,5 ]
Xu, Guowang [3 ]
Verpoorte, Rob [2 ]
机构
[1] Leiden Univ, Leiden Amsterdam Ctr Drug Res, Div Analyt Biosci, NL-2300 RA Leiden, Netherlands
[2] Leiden Univ, Inst Biol, Div Pharmacol, NL-2300 RA Leiden, Netherlands
[3] Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R & A Ctr, Dalian 116023, Peoples R China
[4] TNQ Qual Life, NL-2333 CK Leiden, Netherlands
[5] SU Biomed, NL-3700 AJ Zeist, Netherlands
关键词
ginsenosides; metabolomics; mass spectrometry; Panax ginseng;
D O I
10.1002/pca.1049
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This review summarises the most recent developments in ginseng analysis, in particular the novel approaches in sample pre-treatment and the use of high-performance liquid-chromatography-mass spectrometry. The review also presents novel data on analysing ginseng extracts by nuclear magnetic resonance spectroscopy and high-resolution mass spectrometry (Fourier transform mass spectrometry) in the context of metabolomics. Copyright (C) 2007 John Wiley & Sons, Ltd.
引用
收藏
页码:2 / 16
页数:15
相关论文
共 72 条
[1]   Transformation of ginseng saponins to ginsenoside Rh2 by acids and human intestinal bacteria and biological activities of their transformants [J].
Bae, EA ;
Han, MJ ;
Kim, EJ ;
Kim, DH .
ARCHIVES OF PHARMACAL RESEARCH, 2004, 27 (01) :61-67
[2]   Structural changes of polyacetylenes in American ginseng root can be observed in situ by using Raman spectroscopy [J].
Baranska, Malgorzata ;
Schulz, Hartwig ;
Christensen, Lars P. .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2006, 54 (10) :3629-3635
[3]   NMR-based metabonomic studies on the biochemical effects of commonly used drug carrier vehicles in the rat [J].
Beckwith-Hall, BM ;
Holmes, E ;
Lindon, JC ;
Gounarides, J ;
Vickers, A ;
Shapiro, M ;
Nicholson, JK .
CHEMICAL RESEARCH IN TOXICOLOGY, 2002, 15 (09) :1136-1141
[4]   Liquid chromatography-electrospray ionization mass spectrometry for metabolism and pharmacokinetic studies of ginsenoside Rg3 [J].
Cai, ZW ;
Qian, TX ;
Wong, RNS ;
Jiang, ZH .
ANALYTICA CHIMICA ACTA, 2003, 492 (1-2) :283-293
[5]   Determination of the antioxidant capacity of samples of different types of tea, or of beverages based on tea or other herbal products, using a superoxide dismutase biosensor [J].
Campanella, L ;
Bonanni, A ;
Tomassetti, M .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2003, 32 (4-5) :725-736
[6]   Differentiation and authentication of Panax ginseng, Panax quinquefolius, and ginseng products by using HPLC/MS [J].
Chan, TWD ;
But, PPH ;
Cheng, SW ;
Kwok, IMY ;
Lau, FW ;
Xu, HX .
ANALYTICAL CHEMISTRY, 2000, 72 (06) :1281-1287
[7]   Pressurized liquid extraction of active ingredients (ginsenosides) from medicinal plants using non-ionic surfactant solutions [J].
Choi, MPK ;
Chan, KKC ;
Leung, HW ;
Huie, CW .
JOURNAL OF CHROMATOGRAPHY A, 2003, 983 (1-2) :153-162
[8]   Simultaneous determination of ginsenosides and polyacetylenes in American ginseng root (Panax quinquefolium L.) by high-performance liquid chromatography [J].
Christensen, Lars P. ;
Jensen, Martin ;
Kidmose, Ulla .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2006, 54 (24) :8995-9003
[9]   Simplified extraction of ginsenosides from American ginseng (Panax quinquefolius L.) for high-performance liquid chromatography-ultraviolet analysis [J].
Corbit, RM ;
Ferreira, JFS ;
Ebbs, SD ;
Murphy, LL .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2005, 53 (26) :9867-9873
[10]  
*DIR QUAL MED COUN, 2004, EUR PHARM, V2, P1650