Synthesis of cationic lipids from 1,2,4-butanetriol

被引:35
作者
Ren, T [1 ]
Liu, DX [1 ]
机构
[1] Univ Pittsburgh, Sch Pharm, Dept Pharmaceut Sci, Pittsburgh, PA 15261 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S0040-4039(98)02381-8
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Starting from 1,2,4-butanetriol, a series of quaternary ammonium lipids with diether, ether/ester, and diester bonds as linkage between the hydrocarbon chains and butane backbone were synthesized for gene delivery. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:209 / 212
页数:4
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