Synthesis of cationic lipids from 1,2,4-butanetriol

被引：35

作者：

Ren, T ^{[1
]}

Liu, DX ^{[1
]}

机构：

[1] Univ Pittsburgh, Sch Pharm, Dept Pharmaceut Sci, Pittsburgh, PA 15261 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(98)02381-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Starting from 1,2,4-butanetriol, a series of quaternary ammonium lipids with diether, ether/ester, and diester bonds as linkage between the hydrocarbon chains and butane backbone were synthesized for gene delivery. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：209 / 212

页数：4

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