The NEDICES cohort of the elderly methodology and main neurological findings

被引:63
作者
Bermejo-Pareja, F. [1 ]
Benito-Leon, J. [1 ]
Vega-Q, S. [3 ]
Diaz-Guzman, J. [1 ]
Rivera-Navarro, J. [4 ]
Molina, J. A. [1 ]
Olazaran-Rodriguez, J. [2 ]
Morales-Gonzalez, J. M. [5 ]
机构
[1] Hosp Univ 12 de Octubre, Serv Neurol, E-28001 Madrid, Spain
[2] Hosp Univ Gregorio Maranon, Serv Neurol, Madrid, Spain
[3] Hosp Univ Gregorio Maranon, Ctr Salud El Espinar, Madrid, Spain
[4] Univ Salamanca, Fac Ciencias Sociales, E-37008 Salamanca, Spain
[5] Minist Trabajo & Asuntos Sociales, Area Estudios & Formac, Madrid, Spain
关键词
chronic neurological diseases; cohort; dementia; epidemiology; methods; parkinsonism; population-based study; tremor; stroke;
D O I
10.33588/rn.4607.2008134
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Aim. To summarise the methodological aspects and main findings of the NEDICES (Neurological Disorders in Central Spain) cohort study of the elderly population, with over 5000 participants. Development. The article outlines the findings concerning the following chronic neurological diseases (CND): dementia, Parkinson's disease and Parkinsonisms, stroke and essential, or senile, tremor The NEDICES study examined the health, mortality and a series of sociological aspects of the cohort that are not discussed here. The paper does describe, however the objectives, methods, population and development, with the baseline (1994) and incidence (1997) cut-off points, and the main findings regarding the CND under study are discussed. Conclusions. The prevalence and incidence of the CND are comparable to those of other Spanish and European population-based studies, but with certain peculiarities, such as the fact that incidence of senile tremor is the highest of those reported in the literature and that this CND is associated with dementia. Over half the cases of Parkinson's disease were reported de novo with the study and Alzheimer's disease was associated with vascular risk factors.
引用
收藏
页码:416 / 423
页数:8
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