Signaling takes a breath - New quantitative perspectives on bioenergetics and signal transduction

被引：115

作者：

Krauss, S

Brand, MD

Buttgereit, F

机构：

[1] Beth Israel Deaconess Med Ctr, Dept Med, Div Endocrinol & Metab, Boston, MA 02215 USA

[2] Harvard Univ, Sch Med, Boston, MA 02215 USA

[3] MRC, Dynn Human Nutr Unit, Cambridge CB2 2XY, England

[4] Humboldt Univ, Charite Univ Hosp, Dept Rheumatol & Clin Immunol, D-10117 Berlin, Germany

来源：

IMMUNITY | 2001年 / 15卷 / 04期

关键词：

D O I：

10.1016/S1074-7613(01)00205-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Immune cells are in constant need of energy for both basic housekeeping and specific immune functions. Increased energy demand during lymphocyte stimulation is coordinated by signal transduction pathways. This review explores the interface between lymphocyte signaling and energy metabolism. In particular, it discusses recent work that allows weighing signaling routes with respect to their role in the regulation of energy metabolism during lymphocyte activation.

引用

页码：497 / 502

页数：6

共 21 条

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