Synthetic studies on the sarcodictyins: synthesis of fully functionalized cyclization precursors

被引：32

作者：

Ceccarelli, SM

Piarulli, U

Gennari, C

机构：

[1] Univ Milan, Dipartimento Chim Organ & Ind, CNR, Ctr Studio Sostanze Organ Nat, I-20133 Milan, Italy

[2] Univ Insubria, Dipartimento Sci Mat Fis & Chim, I-22100 Como, Italy

来源：

TETRAHEDRON | 2001年 / 57卷 / 40期

关键词：

sarcodictyins; epoxidation; Wittig reaction; total synthesis;

D O I：

10.1016/S0040-4020(01)00739-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A strategy featuring a key retrosynthetic disconnection at the C2-C3 position was applied to the total synthesis of the common diterpenoid tricyclic skeleton of sarcodictyins and eleutherobin. Fully functionalized cyclization precursors were accessed via a brief and convergent route, making use of unprecedented synthetic transformations. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

收藏

页码：8531 / 8542

页数：12

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