Neurological outcome in isolated congenital heart block and hydrops fetalis

被引：9

作者：

Breur, Johannes M. P. J.

Gooskens, Rob H. J. M.

Kapusta, Livia

Stoutenbeek, Philip

Visser, Gerard H. A.

van den Berg, Paul

Meijboom, Erik J.

机构：

[1] Univ Med Ctr, Wilhelmina Childrens Hosp, Dept Obstet, Utrecht, Netherlands

[2] Univ Med Ctr, Wilhelmina Childrens Hosp, Dept Pediat Neurol, Utrecht, Netherlands

[3] Radboud Univ Nijmegen Med Ctr, Dept Obstet, Nijmegen, Netherlands

[4] Radboud Univ Nijmegen Med Ctr, Childrens Heart Ctr, Nijmegen, Netherlands

[5] Cent Univ Hosp Vaud, Div Pediat Cardiol, Lausanne, Switzerland

来源：

FETAL DIAGNOSIS AND THERAPY | 2007年 / 22卷 / 06期

关键词：

heart block; atrioventricular block; congenital heart block; pediatric cardiology; neurological outcome; congenital heart block/fetal hydrops; fetal hydrops;

D O I：

10.1159/000106355

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: Isolated fetal heart block ( HB), a condition associated with fetal hydrops, carries a high mortality rate and may result in neurodevelopmental sequelae. To the best of our knowledge, no data exist regarding the long- term outcome of such hydropic fetuses. We reviewed our experience with this condition to determine the neurodevelopmental outcome of prenatally diagnosed cases with isolated HB complicated by hydrops fetalis. Methods: Neurodevelopmental assessment of 5 children presented prenatally with isolated HB associated with hydrops fetalis. Results: During the last 18 years, 10 cases were detected prenatally with isolated HB and hydrops fetalis. 3 of the 10 fetuses died in utero, and 2 died postnatally, due to a dilated cardiomyopathy, at the age of 9 months and 4 years, respectively. Neurodevelopmental studies done on the 5 remaining children were normal. Conclusion: Long- term neurodevelopmental assessments of 5 surviving cases presented prenatally with isolated HB and hydrops fetalis are reassuring. Copyright (C) 2007 S. Karger AG, Basel.

引用

页码：457 / 461

页数：5

共 24 条

[1] Normal neuropsychological development in children with congenital complete heart block who may or may not be exposed to high-dose dexamethasone in utero [J].