Pattern of recurrence after surgery in adenocarcinoma of the gastro-oesophageal junction

被引:61
作者
de Manzoni, G
Pedrazzani, C
Pasini, F
Durante, E
Gabbani, M
Grandinetti, A
Guglielmi, A
Griso, C
Cordiano, C
机构
[1] Univ Verona, Dept Gen Surg 1, Div Med Oncol, I-37100 Verona, Italy
[2] Univ Verona, Dept Gen Surg 1, Div Radiat Oncol, I-37100 Verona, Italy
来源
EUROPEAN JOURNAL OF SURGICAL ONCOLOGY | 2003年 / 29卷 / 06期
关键词
gastro-oesophageal junction adenocarcinoma; Siewert classification; surgical treatment; recurrence;
D O I
10.1016/S0748-7983(03)00098-2
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Aims: This study reports mode, timing and predictive factors of recurrence after curative surgery for cardia cancer. Methods: A prospective study in a series of 92 curatively (R0) resected patients from 1988 to 2002. Results: The 5-year recurrence rate was 71%. Lymph node involvement was the only predictor of recurrence. No patients with more than 6 metastatic nodes were free from relapse 2 years after surgery. Locoregional, peritoneal and haematogenous relapses showed a similar median recurrence time (12, 10 and 12 months, respectively), 80% occurred within 24 months. Conclusions: Few patients can be cured by surgery, lymph nodal involvement is the only predictor of recurrence. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:506 / 510
页数:5
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