Treatment with tigecycline of recurrent urosepsis caused by extended-spectrum-β-lactamase-producing Escherichia coli

被引:23
作者
Krueger, Wolfgang A. [1 ]
Kempf, Volkhard A. J. [3 ]
Peiffer, Manou [1 ]
Nagele, Udo [2 ]
Unertl, Klaus E. [1 ]
Schroeder, Torsten H. [1 ]
机构
[1] Tubingen Univ Hosp, Dept Anesthesiol & Intens Care Med, D-72076 Tubingen, Germany
[2] Tubingen Univ Hosp, Dept Urol, D-72076 Tubingen, Germany
[3] Tubingen Univ Hosp, Inst Med Microbiol & Hyg, D-72076 Tubingen, Germany
关键词
D O I
10.1128/JCM.01340-07
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A 25-year-old female was admitted to our intensive care unit with septic shock and multiorgan failure caused by extended-spectrum beta-lactamase-producing Escherichia coli originating from the right renal pelvis. A 16-day course of treatment with meropenem reversed the septic condition, but the infection recurred thereafter. The patient recovered fully after therapy was changed to tigecycline.
引用
收藏
页码:817 / 820
页数:4
相关论文
共 7 条
[1]   Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock [J].
Dellinger, RP ;
Carlet, JM ;
Masur, H ;
Gerlach, H ;
Calandra, T ;
Cohen, J ;
Gea-Banacloche, J ;
Keh, D ;
Marshall, JC ;
Parker, MM ;
Ramsay, G ;
Zimmerman, JL ;
Vincent, JL ;
Levy, MM .
INTENSIVE CARE MEDICINE, 2004, 30 (04) :536-555
[2]   Evaluation by Monte Carlo simulation of the pharmacokinetics of two doses of meropenem administered intermittently or as a continuous infusion in healthy volunteers [J].
Krueger, WA ;
Bulitta, J ;
Kinzig-Schippers, M ;
Landersdorfer, C ;
Holzgrabe, U ;
Naber, KG ;
Drusano, GL ;
Sörgel, F .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (05) :1881-1889
[3]   Correlation of meropenem plasma levels with pharmacodynamic requirements in critically ill patients receiving continuous veno-venous hemofiltration [J].
Krueger, WA ;
Neeser, G ;
Schuster, H ;
Schroeder, TH ;
Hoffmann, E ;
Heininger, A ;
Dieterich, HJ ;
Forst, H ;
Unertl, KE .
CHEMOTHERAPY, 2003, 49 (06) :280-286
[4]   Pharmacokinetics of meropenem in critically ill patients with acute renal failure treated by continuous hemodiafiltration [J].
Krueger, WA ;
Schroeder, TH ;
Hutchison, M ;
Hoffmann, E ;
Dieterich, HJ ;
Heininger, A ;
Erley, C ;
Wehrle, A ;
Unertl, K .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1998, 42 (09) :2421-2424
[5]   The pharmacokinetic and pharmacodynamic profile of tigecycline [J].
Meagher, AK ;
Ambrose, PG ;
Grasela, TH ;
Ellis-Grosse, EJ .
CLINICAL INFECTIOUS DISEASES, 2005, 41 :S333-S340
[6]   Continuous infusion of β-lactam antibiotics in severe infections:: a review of its role [J].
Roberts, Jason A. ;
Paratz, Jennifer ;
Paratz, Elizabeth ;
Krueger, Wolfgang A. ;
Lipman, Jeffrey .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2007, 30 (01) :11-18
[7]   Correlation between candiduria and departmental antibiotic use [J].
Weinberger, M ;
Sweet, S ;
Leibovici, L ;
Pitlik, SD ;
Samra, Z .
JOURNAL OF HOSPITAL INFECTION, 2003, 53 (03) :183-186