Food allergy as a risk factor for asthma morbidity in adults

被引:37
作者
Berns, Stephen H.
Halm, Ethan A.
Sampson, Hugh A.
Sicherer, Scott H.
Busse, Paula J.
Wisnivesky, Juan P. [1 ]
机构
[1] Mt Sinai Sch Med, Dept Med, Div Pulm Crit Care & Sleep Med, New York, NY 10029 USA
[2] Mt Sinai Sch Med, Div Gen Internal Med, New York, NY USA
[3] Mt Sinai Sch Med, Dept Hlth Policy, New York, NY USA
[4] Mt Sinai Sch Med, Dept Pediat, Div Allergy & Immunol, New York, NY USA
[5] Mt Sinai Sch Med, Dept Med, Div Clin Immunol, New York, NY USA
关键词
asthma; food allergy; morbidity; outcomes; risk factors;
D O I
10.1080/02770900701364031
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Background. The objective of this study was to evaluate the relationship between food allergy and asthma morbidity in adults. Methods. We interviewed a cohort of persistent asthmatics from an inner-city clinic. Allergies to food were assessed by patient report of convincing symptoms of acute allergic reactions. Outcome variables included health resource utilization and medication use. Results. The prevalence of allergy to fish, peanut, tree-nut, shellfish, and seed allergies were 3%, 3%, 3%, 13%, and 1%. Patients with allergies to > 1 food had increased asthma hospitalizations, ED visits, and use of oral steroids (p < 0.05 for all comparisons). Specifically, allergy to fish was associated with a greater risk of health resource utilization and increased frequency of oral steroid use (p <= 0.03 for all comparisons). Conclusions. Self-reported allergy to foods was associated with worse outcomes, suggesting that food allergy may be a risk factor for increased asthma morbidity in adults.
引用
收藏
页码:377 / 381
页数:5
相关论文
共 39 条
[1]   Factors associated with hospital admissions and repeat emergency department visits for adults with asthma [J].
Adams, RJ ;
Smith, BJ ;
Ruffin, RE .
THORAX, 2000, 55 (07) :566-573
[2]  
Bjornsson E, 1996, ANN ALLERG ASTHMA IM, V77, P327
[3]   Fatalities due to anaphylactic reactions to foods [J].
Bock, SA ;
Muñoz-Furlong, A ;
Sampson, HA .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2001, 107 (01) :191-193
[4]   THE NATURAL-HISTORY OF PEANUT ALLERGY [J].
BOCK, SA ;
ATKINS, FM .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1989, 83 (05) :900-904
[5]  
BOCK SA, 1988, J ALLERGY CLIN IMMUN, V82, P986
[6]   ASSOCIATION OF ASTHMA WITH SERUM IGE LEVELS AND SKIN-TEST REACTIVITY TO ALLERGENS [J].
BURROWS, B ;
MARTINEZ, FD ;
HALONEN, M ;
BARBEE, RA ;
CLINE, MG .
NEW ENGLAND JOURNAL OF MEDICINE, 1989, 320 (05) :271-277
[7]   Allergen sensitization evaluation and allergen avoidance education in an inner-city adult cohort with persistent asthma [J].
Busse, PJ ;
Wang, JJ ;
Halm, EA .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2005, 116 (01) :146-152
[8]   Asthma in older patients - Factors associated with hospitalization [J].
Diette, GB ;
Krishnan, JA ;
Dominici, F ;
Haponik, E ;
Skinner, EA ;
Steinwachs, D ;
Wu, AW .
ARCHIVES OF INTERNAL MEDICINE, 2002, 162 (10) :1123-1132
[9]   Risk factors for hospitalization among adults with asthma: the influence of sociodemographic factors and asthma severity [J].
Eisner, MD ;
Katz, PP ;
Yelin, EH ;
Shiboski, SC ;
Blanc, PD .
RESPIRATORY RESEARCH, 2001, 2 (01) :53-60
[10]   T helper-2 immunity regulates bronchial hyperresponsiveness in eosinophil-associated gastrointestinal disease in mice [J].
Forbes, E ;
Smart, VE ;
D'Aprile, A ;
Henry, P ;
Yang, M ;
Matthaei, KI ;
Rothenberg, ME ;
Foster, PS ;
Hogan, SP .
GASTROENTEROLOGY, 2004, 127 (01) :105-118