Autophagy and cell death: No longer at odds

被引：76

作者：

Bergmann, Andreas ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Biochem & Mol Biol, Houston, TX 77030 USA

来源：

CELL | 2007年 / 131卷 / 06期

关键词：

D O I：

10.1016/j.cell.2007.11.027

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Autophagy has been associated with both cell survival and cell death, but the role of autophagy in cell death has been controversial. In this issue, Berry and Baehrecke (2007) report that autophagy is involved in physiological cell death during Drosophila development and is controlled by similar mechanisms as those that control its function in cell survival.

引用

页码：1032 / 1034

页数：3

共 10 条

[1] How death shapes life during development
Baehrecke, EH
[J]. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2002, 3 (10) : 779 - 787
[2] BERRY DL, 2007, CELL
[3] The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes
Blommaart, EFC
Krause, U
Schellens, JPM
VreelingSindelarova, H
Meijer, AJ
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 243 (1-2): : 240 - 246
[4] A SAGE approach to discovery of genes involved in autophagic cell death
Gorski, SM
Chittaranjan, S
Pleasance, ED
Freeman, JD
Anderson, CL
Varhol, RJ
Coughlin, SM
Zuyderduyn, SD
Jones, SJM
Marra, MA
[J]. CURRENT BIOLOGY, 2003, 13 (04) : 358 - 363
[5] Nonapoptotic functions of caspases: caspases as regulatory molecules for immunity and cell-fate determination
Kuranaga, Erina
Miura, Masayuki
[J]. TRENDS IN CELL BIOLOGY, 2007, 17 (03) : 135 - 144
[6] Cell biology - Autophagy and cancer
Levine, Beth
[J]. NATURE, 2007, 446 (7137) : 745 - 747
[7] Self-eating and self-killing: crosstalk between autophagy and apoptosis
Maiuri, M. Chiara
Zalckvar, Einat
Kimchi, Adi
Kroemer, Guido
[J]. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2007, 8 (09) : 741 - 752
[8] MORPHOLOGY OF VARIOUS TYPES OF CELL DEATH IN PRENATAL TISSUES
SCHWEICHEL, JU
MERKER, HJ
[J]. TERATOLOGY, 1973, 7 (03) : 253 - 266
[9] Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death
Scott, Ryan C.
Juhasz, Gabor
Neufeld, Thomas P.
[J]. CURRENT BIOLOGY, 2007, 17 (01) : 1 - 11
[10] Autophagosome formation: Core machinery and adaptations
Xie, Zhiping
Klionsky, Daniel J.
[J]. NATURE CELL BIOLOGY, 2007, 9 (10) : 1102 - 1109

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