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Protein adsorption on materials surfaces with nano-topography

被引：62
作者：
Song Wei
Chen Hong [1 ]
机构：
[1] Wuhan Univ Technol, Sch Mat Sci & Engn, Wuhan 430070, Peoples R China
[2] Wuhan Univ Technol, State Key Lab Adv Technol Mat Synth & Proc, Wuhan 430070, Peoples R China
来源：
CHINESE SCIENCE BULLETIN | 2007年 / 52卷 / 23期
基金：
中国国家自然科学基金;
关键词：
nano-topography; protein adsorption; biocompatibility; materials surfaces; NANOMETER-SCALE; SILICONE SURFACES; CHEMISTRY; IMMOBILIZATION; ROUGHNESS; TITANIUM; BEHAVIOR; CELLS;
D O I：
10.1007/s11434-007-0504-6
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];
摘要：
Protein adsorption behavior on the surfaces of biomedical materials is highly related to the biocompatibility of the materials. In the past, numerous research reports were mainly focused on the effect of chemical components of a material's surface on protein adsorption. The effect of surface topography on protein adsorption, the topic of this review, has recently received keen interest. The influence of surface nano-topographic factors, including roughness, curvature and geometry, on protein adsorption as well as the protein adsorption behavior, such as the amount of protein adsorbed, the activity and morphology of adsorbed protein, is introduced.
引用
收藏
页码：3169 / 3173
页数：5
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