A global health problem caused by arsenic from natural sources

被引：691

作者：

Ng, JC ^{[1
]}

Wang, JP ^{[1
]}

Shraim, A ^{[1
]}

机构：

[1] Univ Queensland, Natl Res Ctr Environm Toxicol, Brisbane, Qld 4108, Australia

来源：

CHEMOSPHERE | 2003年 / 52卷 / 09期

关键词：

arsenic; coal; speciation; environmental health; arsenicosis; arsenism; carcinogen; cancer;

D O I：

10.1016/S0045-6535(03)00470-3

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 [工学]; 0830 [环境科学与工程];

摘要：

Arsenic is a carcinogen to both humans and animals. Arsenicals have been associated with cancers of the skin, lung, and bladder. Clinical manifestations of chronic arsenic poisoning include non-cancer end point of hyper- and hypo-pigmentation, keratosis, hypertension, cardiovascular diseases and diabetes. Epidemiological evidence indicates that arsenic concentration exceeding 50 mug l(-1) in the drinking water is not public health protective. The current WHO recommended guideline value for arsenic in drinking water is 10 mug l(-1), whereas many developing countries are still having a value of 50 mug 1(-1). It has been estimated that tens of millions of people are. at risk exposing to excessive levels of arsenic from both contaminated water and arsenic-bearing coal from natural sources. The global health implication and possible intervention strategies were also discussed in this review article. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：1353 / 1359

页数：7

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