Protein-protein interaction networks and biology - what's the connection?

被引：141

作者：

Hakes, Luke ^{[1
]}

Pinney, John W. ^{[1
]}

Robertson, David L. ^{[1
]}

Lovell, Simon C. ^{[1
]}

机构：

[1] Univ Manchester, Fac Life Sci, Manchester M13 9PT, Lancs, England

来源：

NATURE BIOTECHNOLOGY | 2008年 / 26卷 / 01期

基金：

英国惠康基金; 英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1038/nbt0108-69

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Analysis of protein-protein interaction networks is an increasingly popular means to infer biological insight, but is close enough attention being paid to data handling protocols and the degree of bias in the data?.

引用

页码：69 / 72

页数：4

共 35 条

[1] LGL: Creating a map of protein function with an algorithm for visualizing very large biological networks [J].

Adai, AT ;

Date, SV ;

Wieland, S ;

Marcotte, EM .

JOURNAL OF MOLECULAR BIOLOGY, 2004, 340 (01) :179-190

[2] Error and attack tolerance of complex networks [J].

Albert, R ;

Jeong, H ;

Barabási, AL .

NATURE, 2000, 406 (6794) :378-382

[3] Potential artefacts in protein-interaction networks [J].

Aloy, P ;

Russell, RB .

FEBS LETTERS, 2002, 530 (1-3) :253-254

[4]

[Anonymous], NETWORK ANAL

[5] Network biology:: Understanding the cell's functional organization [J].

Barabási, AL ;

Oltvai, ZN .

NATURE REVIEWS GENETICS, 2004, 5 (02) :101-U15

[6] Emergence of scaling in random networks [J].

Barabási, AL ;

Albert, R .

SCIENCE, 1999, 286 (5439) :509-512

[7] Still stratus not altocumulus: Further evidence against the date/party hub distinction [J].

Batada, Nizar N. ;

Reguly, Teresa ;

Breitkreutz, Ashton ;

Boucher, Lorrie ;

Breitkreutz, Bobby-Joe ;

Hurst, Laurence D. ;

Tyers, Mike .

PLOS BIOLOGY, 2007, 5 (06) :1202-1206

[8] Evolutionary and physiological importance of hub proteins [J].

Batada, Nizar N. ;

Hurst, Laurence D. ;

Tyers, Mike .

PLOS COMPUTATIONAL BIOLOGY, 2006, 2 (07) :748-756

[9] Stratus not altocumulus: A new view of the yeast protein interaction network [J].

Batada, Nizar N. ;

Reguly, Teresa ;

Breitkreutz, Ashton ;

Boucher, Lorrie ;

Breitkreutz, Bobby-Joe ;

Hurst, Laurence D. ;

Tyers, Mike .

PLOS BIOLOGY, 2006, 4 (10) :1720-1731

[10] Structure and evolution of protein interaction networks:: a statistical model for link dynamics and gene duplications -: art. no. 51 [J].

Berg, J ;

Lässig, M ;

Wagner, A .

BMC EVOLUTIONARY BIOLOGY, 2004, 4 (1)

← 1 2 3 4 →