Vairiable selection for multivariate failure time data

被引:71
作者
Cai, JW [1 ]
Fan, JQ
Li, RZ
Zhou, HB
机构
[1] Univ N Carolina, Dept Biostat, Chapel Hill, NC 27599 USA
[2] Princeton Univ, Dept Operat Res & Financial Engn, Princeton, NJ 08544 USA
[3] Penn State Univ, Dept Stat, University Pk, PA 16802 USA
关键词
Cox's model; marginal hazards model; penalised likelihood; smoothly clipped absolute deviation; variable selection;
D O I
10.1093/biomet/92.2.303
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In this paper, we propose a penalised pseudo-partial likelihood method for variable selection with multivariate failure time data with a growing number of regression coefficients. Under certain regularity conditions, we show the consistency and asymptotic normality of the penalised likelihood estimators. We further demonstrate that, for certain penalty functions with proper choices of regularisation parameters, the resulting estimator can correctly identify the true model, as if it were known in advance. Based on a simple approximation of the penalty function, the proposed method can be easily carried out with the Newton-Raphson algorithm. We conduct extensive Monte Carlo simulation studies to assess the finite sample performance of the proposed procedures. We illustrate the proposed method by analysing a dataset from the Framingham Heart Study.
引用
收藏
页码:303 / 316
页数:14
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