Complex effects of general anesthesia on sensory processing in the spinal dorsal horn

被引：8

作者：

Yanagidani, T ^{[1
]}

Ota, K ^{[1
]}

Collins, JG ^{[1
]}

机构：

[1] Yale Univ, Dept Anesthesiol, New Haven, CT 06520 USA

来源：

BRAIN RESEARCH | 1998年 / 812卷 / 1-2期

关键词：

anesthetic; volatile; enflurane; spinal cord; LT neuron; WDR neuron; receptive field;

D O I：

10.1016/S0006-8993(98)00938-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A chronic animal preparation allowed us to compare activity of the same single, spinal dorsal horn neurons in the physiologically intact, awake, drug-free state and in the anesthetized state. The inhalation anesthetic enflurane produced profound, and at times, opposite effects on spinal dorsal horn neuron responses to non-noxious and noxious receptive field stimulation. Some effects would not have been predicted, based upon current understanding of anesthetics. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：301 / 304

页数：4

共 19 条

[1] MORPHINE, BUT NOT INHALATION ANESTHESIA, BLOCKS POSTINJURY FACILITATION - THE ROLE OF PREEMPTIVE SUPPRESSION OF AFFERENT TRANSMISSION [J].

ABRAM, SE ;

YAKSH, TL .

ANESTHESIOLOGY, 1993, 78 (04) :713-721

[2] C-FIBERS PROVIDE A SOURCE OF MASKING INHIBITION TO PRIMARY SOMATOSENSORY CORTEX [J].

CALFORD, MB ;

TWEEDALE, R .

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1991, 243 (1308) :269-275

[3]

COLLINS JG, 1980, J PHARMACOL EXP THER, V213, P337

[4] A TECHNIQUE FOR CHRONIC EXTRACELLULAR RECORDING OF NEURONAL-ACTIVITY IN THE DORSAL HORN OF THE LUMBAR SPINAL-CORD IN DRUG-FREE, PHYSIOLOGICALLY INTACT, CATS [J].

COLLINS, JG .

JOURNAL OF NEUROSCIENCE METHODS, 1985, 12 (04) :277-287

[5] PLASTICITY OF SOME SPINAL DORSAL HORN NEURONS AS REVEALED BY PENTOBARBITAL-INDUCED DISINHIBITION [J].

COLLINS, JG ;

REN, K ;

SAITO, Y ;

IWASAKI, H ;

TANG, J .

BRAIN RESEARCH, 1990, 525 (02) :189-197

[6] EFFECTS OF KETAMINE (CL581) ON CELL RESPONSES TO CUTANEOUS STIMULATIONS IN LAMINAE-IV AND LAMINAE-V IN CATS DORSAL HORN [J].

CONSEILLER, C ;

BENOIST, JM ;

BESSON, JM ;

HAMANN, KF ;

MAILLARD, MC .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1972, 18 (03) :346-+

[7]

DEJONG RH, 1969, ANESTHESIOLOGY, V31, P205

[8] CORRELATION OF ETHRANE ELECTROENCEPHALOGRAM WITH MOTOR ACTIVITY IN CATS [J].

DEJONG, RH ;

HEAVNER, JE .

ANESTHESIOLOGY, 1971, 35 (05) :474-&

[9] THE ROLE OF NMDA AND NON-NMDA EXCITATORY AMINO-ACID RECEPTORS IN THE EXCITATION OF PRIMATE SPINOTHALAMIC TRACT NEURONS BY MECHANICAL, CHEMICAL, THERMAL, AND ELECTRICAL STIMULI [J].

DOUGHERTY, PM ;

PALECEK, J ;

PALECKOVA, V ;

SORKIN, LS ;

WILLIS, WD .

JOURNAL OF NEUROSCIENCE, 1992, 12 (08) :3025-3041

[10]

DRUMMOND JC, 1983, J AM VET MED ASSOC, V182, P1099

← 1 2 →