Unexpected occurrence of plasmid-mediated quinolone resistance determinants in environmental Aeromonas spp.

被引：186

作者：

Cattoir, Vincent ^{[1
,2
]}

Poirel, Laurent ^{[1
]}

Aubert, Camille ^{[1
]}

Soussy, Claude-James ^{[2
]}

Nordmann, Patrice ^{[1
]}

机构：

[1] Hop Bicetre, Inst Natl Sante Rech, Serv Bacteriol Virol Hyg, Med Unite 914, F-94275 Le Kremlin Bicetre, France

[2] Univ Paris 07, F-75221 Paris 05, France

来源：

EMERGING INFECTIOUS DISEASES | 2008年 / 14卷 / 02期

关键词：

D O I：

10.3201/eid1402.070677

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We searched for plasmid-mediated quinolone resistance determinants of the Qnr type in several water samples collected at diverse locations from the Seine River (Paris, France). The qnrS2 genes were identified from Aeromonas punctata subsp. punctata and A. media. The qnrS2 gene was located on lncU-type plasmids in both isolates, which resulted in increased MIC values of quinolones and fluoroquinolones, once they were transferred into Escherichia coli. The qnrS2 gene identified in A. punctata was part of novel genetic structure corresponding to a mobile insertion cassette element. This identification of plasm id-mediated qnr genes outside Enterobacteriaceae underlines a possible diffusion of those resistance determinants within gram-neaative rods.

引用

页码：231 / 237

页数：7

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