Minireview: Intrinsic and Extrinsic Factors in Thyroid Gland Development: An Update

被引：66

作者：

De Felice, Mario ^{[2
,3
]}

Di Lauro, Roberto ^{[1
,2
]}

机构：

[1] Stn Zool Anton Dohrn, I-80121 Naples, Italy

[2] Univ Naples Federico 2, Dipartimento Biol & Patol Cellulare & Mol, I-80131 Naples, Italy

[3] Biogem, I-83031 Ariano Irpino, AV, Italy

来源：

ENDOCRINOLOGY | 2011年 / 152卷 / 08期

关键词：

CONGENITAL HYPOTHYROIDISM; TRANSCRIPTION FACTORS; BRANCHIOSTOMA-LANCEOLATUM; ENDODERM DEVELOPMENT; ASCIDIAN ENDOSTYLE; MONOZYGOTIC TWINS; GENE-EXPRESSION; HEX PROMOTER; LUNG-CANCER; MOUSE MODEL;

D O I：

10.1210/en.2011-0204

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In vertebrates the portion of the thyroid gland synthesizing the thyroid hormones develops from a small group of endodermal cells in the foregut. The nature of the signals that lead to the biochemical and morphogenetic events responsible for the organization of these cells into the adult thyroid gland has only recently become evident. In this review we summarize recent developments in the understanding of these processes, derived from evidence collected in several organisms. (Endocrinology 152: 2948-2956, 2011)

引用

页码：2948 / 2956

页数：9

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