Amphiphilic four-helix bundle peptides designed for light-induced electron transfer across a soft interface

被引：32

作者：

Ye, SX

Discher, BM

Strzalka, J

Xu, T

Wu, SP

Noy, D

Kuzmenko, I

Gog, T

Therien, MJ

Dutton, PL

Blasie, JK ^{[1
]}

机构：

[1] Univ Penn, Dept Chem, Philadelphia, PA 19104 USA

[2] Univ Penn, Dept Biochem & Biophys, Philadelphia, PA 19104 USA

[3] Argonne Natl Lab, Adv Photon Source, Complex Mat Consortium, Argonne, IL 60439 USA

来源：

NANO LETTERS | 2005年 / 5卷 / 09期

关键词：

D O I：

10.1021/nl050542k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A family of four-helix bundle peptides were designed to be amphiphilic, possessing distinct hydrophilic and hydrophobic domains along the length of the bundle's exterior. This facilitates their vectorial insertion across a soft interface between polar and nonpolar media. Their design also now provides for selective incorporation of electron donor and acceptor cofactors within each domain. This allows translation of the designed intramolecular electron transfer along the bundle axis into a macroscopic charge separation across the interface.

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收藏

页码：1658 / 1667

页数：10

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