Cardiotoxicity of nano-particles

被引：110

作者：

Bostan, Hasan Badie ^{[1
]}

Rezaee, Ramin ^{[2
,4
]}

Valokala, Mahmoud Gorji ^{[1
]}

Tsarouhas, Konstantinos ^{[3
]}

Golokhvast, Kirill ^{[4
]}

Tsatsakis, Aristidis M. ^{[5
]}

Karimi, Gholamreza ^{[1
]}

机构：

[1] Mashhad Univ Med Sci, Sch Pharm, Pharmaceut Res Ctr, Mashhad, Iran

[2] North Khorasan Univ Med Sci, Sch Med, Dept Physiol & Pharmacol, Bojnurd, Iran

[3] Gen Univ Hosp Larisa, Cardiol Clin, Larisa, Greece

[4] Far Eastern Fed Univ, Sci Educ Ctr Nanotechnol, 10 Pushkinskaya St, Vladivostok 690950, Russia

[5] Univ Crete, Fac Med, Dept Forens Sci & Toxicol, Iraklion 71003, Greece

来源：

LIFE SCIENCES | 2016年 / 165卷

基金：

俄罗斯科学基金会;

关键词：

Nano-particle; Cardiac toxicity; Inflammatory marker; Reactive oxygen species; ZINC-OXIDE NANOPARTICLES; FIBROBLAST-GROWTH-FACTOR; CARDIAC ISCHEMIA/REPERFUSION INJURY; WALLED CARBON NANOTUBES; SILVER NANOPARTICLES; OXIDATIVE STRESS; CARDIOVASCULAR-RESPONSES; DNA-DAMAGE; IN-VITRO; SILICA NANOPARTICLES;

D O I：

10.1016/j.lfs.2016.09.017

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

100103 [病原生物学]; 100218 [急诊医学];

摘要：

Nano-particles (NPs) are used in industrial and biomedical fields such as cosmetics, food additives and biosensors. Beside their favorable properties, nanoparticles are responsible for toxic effects. Local adverse effects and/or systemic toxicity are described with nanoparticle delivery to target organs of the human body. Animal studies provide evidence for the aforementioned toxicity. Cardiac function is a specific target of nanoparticles. Thus, reviewing the current bibliography on cardiotoxicity of nanoparticles and specifically of titanium, zinc, silver, carbon, silica and iron oxide nano-materials is the aim of this study. (C) 2016 Elsevier Inc. All rights reserved.

引用

收藏

页码：91 / 99

页数：9

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