Salpingotomy or salpingectomy in tubal ectopic pregnancy: What do women prefer?

被引:43
作者
van Mello, N. M. [1 ]
Mol, F. [1 ]
Opmeer, B. C. [2 ]
de Bekker-Grob, E. W. [3 ]
Essink-Bot, M. L. [4 ]
Ankum, W. M. [1 ]
Mol, B. W. [1 ]
van der Veen, F. [5 ]
Hajenius, P. J. [1 ]
机构
[1] Univ Amsterdam, Dept Obstet & Gynaecol, Amsterdam, Netherlands
[2] Univ Amsterdam, Acad Med Ctr, Dept Clin Epidemiol & Biostat, NL-1105 AZ Amsterdam, Netherlands
[3] Erasmus MC Univ Med Ctr, Dept Publ Hlth, Rotterdam, Netherlands
[4] Univ Amsterdam, Dept Social Med, NL-1105 AZ Amsterdam, Netherlands
[5] Univ Amsterdam, Acad Med Ctr, Ctr Reprod Med, NL-1105 AZ Amsterdam, Netherlands
关键词
conjoint analysis; discrete choice experiment; ectopic pregnancy; patient preference; salpingectomy; salpingotomy; DRUG-TREATMENT; FERTILITY;
D O I
10.1016/j.rbmo.2010.06.034
中图分类号
R71 [妇产科学];
学科分类号
100211 [妇产科学];
摘要
There is an ongoing debate whether tubal ectopic pregnancy should be treated by salpingotomy or salpingectomy. It is unknown which treatment women prefer in view of the potentially better fertility outcome but disadvantages of salpingotomy. This study investigated women surgically treated for tubal ectopic pregnancy and subfertile women desiring pregnancy and their preferences for salpingotomy relative to salpingectomy by means of a web-based discrete choice experiment consisting of 16 choice sets. Scenarios representing salpingotomy differed in three attributes: intrauterine pregnancy (IUP) chance, risk of persistent trophoblast and risk of repeat ectopic pregnancy. An 'opt out' alternative, representing salpingectomy, was similar for every choice set. A multinomial logistic regression model was used to analyse relative importance of the attributes. This study showed that the negative effect of repeat ectopic pregnancy was 1.6 times stronger on the preference of women compared with the positive effect of the spontaneous IUP rate. For all women, the risk of persistent trophoblast was acceptable if compensated by a small rise in the spontaneous IUP rate. The conclusion was that women preferred avoiding a repeat ectopic pregnancy to a higher probability of a spontaneous IUP in the surgical treatment of tubal ectopic pregnancy. (C) 2010, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:687 / 693
页数:7
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