Current concepts in antibiotic-resistant Gram-negative bacteria

被引：50

作者：

Torres, Julian Andres ^{[1
]}

Villegas, Maria Virginia ^{[1
]}

Quinn, Andjohn P. ^{[1
]}

机构：

[1] Chicago Infect Dis Res Inst, Chicago, IL 60612 USA

来源：

EXPERT REVIEW OF ANTI-INFECTIVE THERAPY | 2007年 / 5卷 / 05期

关键词：

bacterial resistance; carbapenems; Gram-negatives; mechanisms of resistance; tigecycline; MEDIATED QUINOLONE RESISTANCE; METALLO-BETA-LACTAMASE; ACINETOBACTER-BAUMANNII; PSEUDOMONAS-AERUGINOSA; CARBAPENEM RESISTANCE; ESCHERICHIA-COLI; EFFLUX PUMPS; IN-VITRO; OXA-23; CARBAPENEMASE; MULTIDRUG-RESISTANCE;

D O I：

10.1586/14787210.5.5.833

中图分类号：

R51 [传染病];

学科分类号：

100201 [内科学];

摘要：

Gram-negative bacteria are the dominant killers among bacterial pathogens in the intensive care unit. Antibiotic resistance has become a threat in hospital settings and efforts are being made to understand the underlying mechanisms. This review describes current data on the most important mechanisms of resistance in prevalent Gram-negative pathogens as well as newer therapeutic options.

引用

页码：833 / 843

页数：11

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