The cell biology of smell

被引：105

作者：

DeMaria, Shannon

Ngai, John ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Cell & Mol Biol, Helen Wills Neurosci Inst, Berkeley, CA 94720 USA

来源：

JOURNAL OF CELL BIOLOGY | 2010年 / 191卷 / 03期

关键词：

OLFACTORY SENSORY NEURONS; ODORANT RECEPTOR GENES; FUNCTIONAL EXPRESSION; AXON GUIDANCE; CHEMOSENSORY RECEPTORS; TOPOGRAPHIC MAP; MICE DEFICIENT; MOUSE; BULB; ORGANIZATION;

D O I：

10.1083/jcb.201008163

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The olfactory system detects and discriminates myriad chemical structures across a wide range of concentrations To meet this task, the system utilizes a large family of G protein coupled receptors the odorant receptors which are the chemical sensors underlying the perception of smell Interestingly, the odorant receptors are also involved in a number of developmental decisions, including the regulation of their own expression and the patterning of the olfactory sensory neurons' synaptic connections in the brain This review will focus on the diverse roles of the odorant receptor in the function and development of the olfactory system

引用

页码：443 / 452

页数：10

共 74 条

[1] Functional analysis of a mammalian odorant receptor subfamily [J].