Kruppel-like transcription factors and control of pluripotency

被引：44

作者：

Bourillot, Pierre-Yves

Savatier, Pierre ^{[1
]}

机构：

[1] INSERM, U846, F-69500 Bron, France

来源：

BMC BIOLOGY | 2010年 / 8卷

关键词：

STEM-CELL DIFFERENTIATION; SELF-RENEWAL; MOUSE;

D O I：

10.1186/1741-7007-8-125

中图分类号：

Q [生物科学];

学科分类号：

090105 [作物生产系统与生态工程];

摘要：

Recent papers have demonstrated a role for Kruppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripotency. However, it is not clear whether each factor has a unique role or whether they are functionally redundant. A paper by Parisi and colleagues in BMC Biology now sheds light on the mechanism by which Klf5 regulates pluripotency.

引用

页数：3

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