Time-gated biological imaging by use of colloidal quantum dots

被引：274

作者：

Dahan, M

Laurence, T

Pinaud, F

Chemla, DS

Alivisatos, AP

Sauer, M

Weiss, S

机构：

[1] Univ Calif Berkeley, Lawrence Berkeley Lab, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

[3] Univ Heidelberg, Inst Phys Chem, D-69120 Heidelberg, Germany

来源：

OPTICS LETTERS | 2001年 / 26卷 / 11期

关键词：

D O I：

10.1364/OL.26.000825

中图分类号：

O43 [光学];

学科分类号：

070207 [光学]; 0803 [光学工程];

摘要：

The long (but not too long) fluorescence lifetime of CdSe semiconductor quantum dots was exploited to enhance fluorescence biological imaging contrast and sensitivity by time-gated detection. Significant and selective reduction of the autofluorescence contribution to the overall image was achieved, and enhancement of the signal-to-background ratio by more than an order of magnitude was demonstrated. (C) 2001 Optical Society of America.

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收藏

页码：825 / 827

页数：3

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