Comparison of predicted with observed biokinetics of inhaled plutonium nitrate and gadolinium oxide in humans

被引：5

作者：

Hodgson, A ^{[1
]}

Shutt, AL

Etherington, G

Hodgson, SA

Rance, E

Stradling, GN

Youngman, MJ

Ziesenis, A

Kreyling, WG

机构：

[1] Natl Radiol Protect Board, Didcot OX11 0RQ, Oxon, England

[2] GSF Forschungszentrum Umwelt & Gesundheit, Inst Inhalat Biol, Neuherberg, Germany

来源：

RADIATION PROTECTION DOSIMETRY | 2003年 / 105卷 / 1-4期

关键词：

D O I：

10.1093/oxfordjournals.rpd.a006328

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The absorption kinetics to blood of plutonium and gadolinium after inhalation as nitrate and oxide in humans and animals has been studied. For each material, values describing the time dependence of absorption were derived from the studies in animals and used with the ICRP human respiratory tract model to predict lung retention and cumulative amounts to blood for the volunteers inhaling the same materials. Comparison with the observed behaviour in the volunteers suggests that absorption of plutonium and gadolinium is reasonably species independent, and that data obtained from animal studies can be used to assess their biokinetic behaviour in humans.

引用

页码：91 / 94

页数：4

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