Parkinson's disease, progressive lumbar kyphosis and focal paraspinal myositis.

被引:14
作者
Charpentier, P
Dauphin, A
Stojkovic, T
Cotten, A
Hurtevent, JF
Maurage, CA
Thévenon, A
Destée, A
Defebvre, L
机构
[1] Ctr Hosp Reg, Neurol Clin, Lille, France
[2] Ctr Hosp Reg, Serv Reeduc Fonct, Lille, France
[3] Ctr Hosp Reg, Serv Imagerie Osteoarticulaire, Lille, France
[4] Ctr Hosp Reg, Serv Neurophysiol Clin, Lille, France
[5] Ctr Hosp Reg, Serv Neuropathol, Lille, France
[6] Univ Lille, Lille, France
关键词
camptocormia; Parkinson's disease; myositis; paraspinal muscles; dystonia;
D O I
10.1016/S0035-3787(05)85077-5
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction. The camptocormia (bent spine) is characterized by a severe forward flexion of the thoracolumbar spine which disappears in the supine position. Clinical cave. We describe a typical case observed in a parkinsonian patient. The MRI, electromyogram and biopsy of the paraspinal muscles revealed a typical myositis pattern. Discussion. This case, the sixth published to our knowledge, confirms that focal myositis is associated with the camptocormia in Parkinson's disease. Typically it is observed in male subjects, appearing 4 to 6 years after the onset of Parkinson's disease, in fluctuating patients treated by an association of L-Dopa and agonist. It appears quickly and becomes the most important symptom. Antiparkinsonian drugs are useless. Conclusion. This exceptional picture raises original pathophysiological and therapeutic questions. Systematic studies should be performed in order to detail the pathophysiological link between these 3 entities: Parkinson's disease, local myositis and camptocormia.
引用
收藏
页码:459 / 463
页数:5
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