Does feeding tube placement predict for long-term swallowing disability after radiotherapy for head and neck cancer?

被引:40
作者
Al-Othman, MOF [1 ]
Amdur, RJ [1 ]
Morris, CG [1 ]
Hinerman, RW [1 ]
Mendenhall, WM [1 ]
机构
[1] Univ Florida, Hlth Sci Ctr, Dept Radiat Oncol, Gainesville, FL 32608 USA
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2003年 / 25卷 / 09期
关键词
D O I
10.1002/hed.10279
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Purpose. To evaluate feeding tube use. Materials and Methods. Nine hundred thirty-four patients were treated with radiotherapy (FIT). Results. Feeding tubes were placed in 235 patients (25%): 212 patients (22.5%) for acute toxicity, 18 patients (2%) for late effects, and 5 patients (0.5%) for both. Median duration of tube dependence for acute toxicity was 3.8 months. Multivariate analysis revealed that feeding tube placement for acute toxicity was increased with higher FIT dose (p < .0001), adjuvant chemotherapy (p = .0002), advanced age (p = .0002), and the presence of neck disease (p = .0045). The risk of a feeding tube for late effects was 2% at 5 years. The likelihood of feeding tube placement for late effects was greater for women (p = .0293), higher FIT dose (p = .0345), and primary sites, including the hypopharynx and multiple synchronous primary tumors (p = .0360). Feeding tube placement for late effects was unrelated to tube placement for acute toxicity. Conclusion. Likelihood of long-term feeding tube dependence was low and unrelated to placement for acute effects. (C) 2003 Wiley Periodicals, Inc.
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页码:741 / 747
页数:7
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