Elevated factor XIII level and the risk of myocardial infarction in women

被引:40
作者
Bereczky, Zsuzsanna [1 ]
Balogh, Emilia [2 ]
Katona, Eva [1 ]
Czuriga, Istvan [2 ]
Edes, Istvan [2 ]
Muszbek, Laszlo [1 ]
机构
[1] Hungarian Acad Sci, Thrombosis & Haemostasis Res Grp, Clin Res Ctr, Debrecen, Hungary
[2] Univ Debrecen, Dept Cardiol, Med & Hlth Sci Ctr, POB 40, H-4012 Debrecen, Hungary
关键词
factor XIII; coronary sclerosis; myocardial infarction; women;
D O I
10.3324/haematol.10647
中图分类号
R5 [内科学];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
Factor XIII (FXIII) activity and antigen levels were determined in 955 patients investigated by coronary angiography. Patients were sub-grouped according to the presence or absence of coronary sclerosis (CS+, CS-) and a positive history of myocardial infarction (MI+, MI-). In females, but not in males, adjusted FXIII activity and antigen levels were significantly elevated in the CS+MI+ group compared to in the CS+MI- group. FXIII levels in the upper tertile were associated with significantly increased risk of MI in females, but not in males.
引用
收藏
页码:287 / 288
页数:2
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