Novel ruthenium- and platinum-catalyzed sequential reactions: Synthesis of tri- and tetrasubstituted furans and pyrroles from propargylic alcohols and ketones

被引：179

作者：

Nishibayashi, Y

Yoshikawa, M

Inada, Y

Milton, MD

Hidai, M ^{[1
]}

Uemura, S

机构：

[1] Tokyo Univ Sci, Dept Mat Sci & Technol, Fac Ind Sci & Technol, Noda, Chiba 2788510, Japan

[2] Kyoto Univ, Dept Energy & Hydrocarbon Chem, Grad Sch Engn, Kyoto 6068501, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 23期

关键词：

domino reactions; heterocycles; homogeneous catalysis; platinum; ruthenium;

D O I：

10.1002/anie.200351170

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two cats. in the same pot: The two catalysts [Cp*RuCl(μ2-SMe)2RuCp*Cl] (1) and PtCl2 (2) promote a sequence of catalytic cycles in the same medium. Trior tetrasubstituted furans or pyrroles are afforded in moderate to good yields with high regioselectivities from the catalyzed reactions of propargylic alcohols with ketones or with ketones and anilines, respectively (see scheme; cats.=catalysts).

引用

页码：2681 / 2684

页数：4

共 66 条

[1]

[Anonymous], 2002, ANGEW CHEM

[2] Hydration of alkynes by a PtCl4-CO catalyst [J].