Efficient route to 7α-(benzoyloxy)-3-dioxolane cholestan-24(R)-ol, a key intermediate in the synthesis of squalamine

被引：54

作者：

Jones, SR

Selinsky, BS ^{[1
]}

Rao, MN

Zhang, XH

Kinney, WA

Tham, FS

机构：

[1] Villanova Univ, Dept Chem, Villanova, PA 19085 USA

[2] Magainin Pharmaceut Inc, Plymouth Meeting, PA USA

[3] Rensselaer Polytech Inst, Dept Chem, Troy, NY USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1998年 / 63卷 / 11期

关键词：

D O I：

10.1021/jo971405d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

收藏

页码：3786 / 3789

页数：4

相关论文

共 14 条

[1] [Anonymous], ORGANIC REACTIONS ST
[2] FORICHER J, 1991, Patent No. 5030739
[3] GAUDRY M, 1988, ORG SYNTH, V6, P193
[4] STEREOSELECTIVE AND REGIOSELECTIVE REDUCTION OF STEROID KETONES BY POTASSIUM TRI(R,S-S-BUTYL)BOROHYDRIDE
GONDOS, G
ORR, JC
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1982, (21) : 1239 - 1240
[5] The synthesis and characterization of analogs of the antimicrobial compound squalamine: 6 beta-hydroxy-3-aminosterols synthesized from hyodeoxycholic acid
Jones, SR
Kinney, WA
Zhang, XH
Jones, LM
Selinsky, BS
[J]. STEROIDS, 1996, 61 (10) : 565 - 571
[6] A CONVENIENT METHOD FOR REDUCTION OF HYDROPEROXIDIC OZONATION PRODUCTS
KNOWLES, WS
THOMPSON, QE
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1960, 25 (06) : 1031 - 1033
[7] LE PH, 1983, THESIS U CALIFORNIA
[8] SQUALAMINE - AN AMINOSTEROL ANTIBIOTIC FROM THE SHARK
MOORE, KS
WEHRLI, S
RODER, H
ROGERS, M
FORREST, JN
MCCRIMMON, D
ZASLOFF, M
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (04) : 1354 - 1358
[9] SYNTHESIS OF SQUALAMINE - A STEROIDAL ANTIBIOTIC FROM THE SHARK
MORIARTY, RM
TULADHAR, SM
GUO, L
WEHRLI, S
[J]. TETRAHEDRON LETTERS, 1994, 35 (44) : 8103 - 8106
[10] MORIARTY RM, 1995, TETRAHEDRON LETT, V36, P5139