Distribution of neurons expressing tyrosine hydroxylase in the human cerebral cortex

被引:37
作者
Benavides-Piccione, Ruth [1 ]
DeFelipe, Javier [1 ]
机构
[1] CSIC, Inst Cajal, E-28002 Madrid, Spain
关键词
catecholamines; cortical specializations; evolution; interneurons;
D O I
10.1111/j.1469-7580.2007.00760.x
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
Since the very first detailed description of the different types of cortical interneurons by Cajal, the tremendous variation in the morphology, physiology and neurochemical properties of these cells has become apparent. However, it still remains unclear whether all types of interneurons are present in all cortical areas and species. Here we have focused on tyrosine hydroxylase (TH)-immunoreactive cortical interneurons, which although only present in certain species, are particularly abundant in the human neocortex. We argue that this type of interneuron is more widespread in the human neocortex than in any other species examined so far and that, therefore, it is probably involved in a larger variety of cortical circuits. In addition, notable regional variation can be seen in relation to these interneurons. These differences further emphasize the variability in the design of microcircuits between cortical areas and species, and they probably reflect an evolutionary adaptation of cortical circuits to particular functions.
引用
收藏
页码:212 / 222
页数:11
相关论文
共 84 条
[1]  
Akil M, 2003, J NEUROSCI, V23, P2008
[2]  
[Anonymous], 1994, Brodmann's localisation in the cerebral cortex
[3]  
[Anonymous], REV CIEN MED BARC
[4]  
[Anonymous], 1891, La Cellule
[5]  
BALLESTEROSYANE.I, 2005, J COMP NEUROL, V486, P344
[6]   Catecholaminergic innervation of pyramidal neurons in the human temporal cortex [J].
Benavides-Piccione, R ;
Arellano, JI ;
DeFelipe, J .
CEREBRAL CORTEX, 2005, 15 (10) :1584-1591
[7]   Different populations of tyrosine-hydroxylase-immunoreactive neurons defined by differential expression of nitric oxide synthase in the human temporal cortex [J].
Benavides-Piccione, R ;
DeFelipe, J .
CEREBRAL CORTEX, 2003, 13 (03) :297-307
[8]   Convergence and plasticity of monoaminergic systems in the medial prefrontal cortex during the postnatal period: Implications for the development of psychopathology [J].
Benes, FM ;
Taylor, JB ;
Cunningham, MC .
CEREBRAL CORTEX, 2000, 10 (10) :1014-1027
[9]  
Berger B., 1994, P293
[10]   REGIONAL AND LAMINAR DISTRIBUTION OF THE DOPAMINE AND SEROTONIN INNERVATION IN THE MACAQUE CEREBRAL-CORTEX - A AUTORADIOGRAPHIC STUDY [J].
BERGER, B ;
TROTTIER, S ;
VERNEY, C ;
GASPAR, P ;
ALVAREZ, C .
JOURNAL OF COMPARATIVE NEUROLOGY, 1988, 273 (01) :99-119