Multilocus genotyping indicates that the ability to invade the bloodstream is widespread among Candida albicans isolates

被引:23
作者
Luu, LN [1 ]
Cowen, LE [1 ]
Sirjusingh, C [1 ]
Kohn, LM [1 ]
Anderson, JB [1 ]
机构
[1] Univ Toronto, Dept Bot, Mississauga, ON L5L 1C6, Canada
关键词
D O I
10.1128/JCM.39.4.1657-1660.2001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Multilocus genotyping was used to compare populations of Candida albicans from oral mucosa and blood. No significant differences in allele frequencies between the two samples were detected, and in a dendrogram of genotypic similarities, genotypes from both types of samples were finely interspersed. This is evidence for widespread distribution of invasive potential.
引用
收藏
页码:1657 / 1660
页数:4
相关论文
共 18 条
  • [2] AN ANIMAL-MODEL FOR OROPHARYNGEAL, ESOPHAGEAL AND GASTRIC CANDIDOSIS
    COLE, GT
    LYNN, KT
    SESHAN, KR
    [J]. MYCOSES, 1990, 33 (01) : 7 - 19
  • [3] COLE GT, 1988, J MED VET MYCOL, V26, P173
  • [4] Multilocus genotypes and DNA fingerprints do not predict variation in azole resistance among clinical isolates of Candida albicans
    Cowen, LE
    Sirjusingh, C
    Summerbell, RC
    Walmsley, S
    Richardson, S
    Kohn, LM
    Anderson, JB
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (12) : 2930 - 2938
  • [5] Evolution of drug resistance in experimental populations of Candida albicans
    Cowen, LE
    Sanglard, D
    Calabrese, D
    Sirjusingh, C
    Anderson, JB
    Kohn, LM
    [J]. JOURNAL OF BACTERIOLOGY, 2000, 182 (06) : 1515 - 1522
  • [6] Molecular markers reveal that population structure of the human pathogen Candida albicans exhibits both clonality and recombination
    Graser, Y
    Volovsek, M
    Arrington, J
    Schonian, G
    Presber, W
    Mitchell, TG
    Vilgalys, R
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (22) : 12473 - 12477
  • [7] Levin Bruce R., 1994, Trends in Microbiology, V2, P76, DOI 10.1016/0966-842X(94)90538-X
  • [8] Towards understanding the evolution of the human commensal yeast Candida albicans
    Lott, TJ
    Holloway, BP
    Logan, DA
    Fundyga, R
    Arnold, J
    [J]. MICROBIOLOGY-UK, 1999, 145 : 1137 - 1143
  • [9] CANDIDA-ALBICANS STRAIN DELINEATION
    MERZ, WG
    [J]. CLINICAL MICROBIOLOGY REVIEWS, 1990, 3 (04) : 321 - 334
  • [10] ANALYSIS OF CANDIDA-ALBICANS PHENOTYPES FROM DIFFERENT GEOGRAPHICAL AND ANATOMICAL SOURCES
    ODDS, FC
    ABBOTT, AB
    STILLER, RL
    SCHOLER, HJ
    POLAK, A
    STEVENS, DA
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1983, 18 (04) : 849 - 857