Vitamin D Insufficiency.

被引：597

作者：

Rosen, Clifford J. ^{[1
]}

机构：

[1] Maine Med Ctr, Res Inst, Scarborough, ME 04074 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2011年 / 364卷 / 03期

关键词：

CIRCULATING 25-HYDROXYVITAMIN D; D SUPPLEMENTATION; SERUM; 25-HYDROXYVITAMIN-D; D DEFICIENCY; CONTROLLED TRIAL; FRACTURE RISK; BONE LOSS; CALCIUM; OLDER; WOMEN;

D O I：

10.1056/NEJMcp1009570

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A healthy 61-year-old white woman is concerned about a low vitamin D level detected during an assessment of her skeletal health. Her menopause began at 54 years of age. She has no history of falls, and there is no family history of hip fracture. She takes no medications or supplements. Her height is 157.5 cm (5 ft 2 in.), and her weight 59.1 kg (130 lb). The results of a physical examination are unremarkable, and the findings on laboratory studies are normal. The T score for bone mineral density at the hip is -1.5, and the serum level of 25-hydroxyvitamin D is 21 ng per milliliter (53 nmol per liter). What do you advise?

引用

页码：248 / 254

页数：7

共 50 条

[1]

[Anonymous], 2010, IOM REP CALC VIT D

[2]

[Anonymous], [No title captured]

[3] 25-Hydroxyvitamin D Measurement, 2009: A Review for Clinicians [J].

Binkley, Neil ;

Krueger, Diane ;

Lensmeyer, Gary .

JOURNAL OF CLINICAL DENSITOMETRY, 2009, 12 (04) :417-427

[4] Effect of vitamin D on falls - A meta-analysis [J].

Bischoff-Ferrari, HA ;

Dawson-Hughes, B ;

Willett, WC ;

Staehelin, HB ;

Bazemore, MG ;

Zee, RY ;

Wong, JB .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 291 (16) :1999-2006

[5] Vitamin D insufficiency and health outcomes over 5 y in older women [J].

Bolland, Mark J. ;

Bacon, Catherine J. ;

Horne, Anne M. ;

Mason, Barbara H. ;

Ames, Ruth W. ;

Wang, Tom K. M. ;

Grey, Andrew B. ;

Gamble, Greg D. ;

Reid, Ian R. .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 2010, 91 (01) :82-89

[6] Effects of vitamin D supplementation and exercise training on physical performance in Chilean vitamin D deficient elderly subjects [J].

Bunout, Daniel ;

Barrera, Gladys ;

Leiva, Laura ;

Gattas, Vivien ;

de la Maza, Maria Pia ;

Avendano, Marcelo ;

Hirsch, Sandra .

EXPERIMENTAL GERONTOLOGY, 2006, 41 (08) :746-752

[7] Serum 25-hydroxyvitamin D concentrations and risk for hip fractures [J].

Cauley, Jane A. ;

LaCroix, Andrea Z. ;

Wu, LieLing ;

Horwitz, Mara ;

Danielson, Michelle E. ;

Bauer, Doug C. ;

Lee, Jennifer S. ;

Jackson, Rebecca D. ;

Robbins, John A. ;

Wu, Chunyuan ;

Stanczyk, Frank Z. ;

LeBoff, Meryl S. ;

Wactawski-Wende, Jean ;

Sarto, Gloria ;

Ockene, Judith ;

Cummings, Steven R. .

ANNALS OF INTERNAL MEDICINE, 2008, 149 (04) :242-+

[8] Serum 25-Hydroxyvitamin D and the Risk of Hip and Nonspine Fractures in Older Men [J].

Cauley, Jane A. ;

Parimi, Neeta ;

Ensrud, Kristine E. ;

Bauer, Douglas C. ;

Cawthon, Peggy M. ;

Cummings, Steven R. ;

Hoffman, Andrew R. ;

Shikany, James M. ;

Barrett-Connor, Elizabeth ;

Orwoll, Eric .

JOURNAL OF BONE AND MINERAL RESEARCH, 2010, 25 (03) :545-553

[9] Prevalence of vitamin D insufficiency in an adult normal population [J].

Chapuy, MC ;

Preziosi, P ;

Maamer, M ;

Arnaud, S ;

Galan, P ;

Hercberg, S ;

Meunier, PJ .

OSTEOPOROSIS INTERNATIONAL, 1997, 7 (05) :439-443

[10] VITAMIN-D(3) AND CALCIUM TO PREVENT HIP-FRACTURES IN ELDERLY WOMEN [J].

CHAPUY, MC ;

ARLOT, ME ;

DUBOEUF, F ;

BRUN, J ;

CROUZET, B ;

ARNAUD, S ;

DELMAS, PD ;

MEUNIER, PJ .

NEW ENGLAND JOURNAL OF MEDICINE, 1992, 327 (23) :1637-1642

← 1 2 3 4 5 →