Live or let die: E2F1 and PI3K pathways intersect to make life or death decisions

被引：15

作者：

Dyniacht, Brian David ^{[1
]}

机构：

[1] NYU, Sch Med, Inst Canc, New York, NY 10016 USA

来源：

CANCER CELL | 2008年 / 13卷 / 01期

关键词：

D O I：

10.1016/j.ccr.2007.12.017

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

In the current issue of Cancer Cell, Hallstrom et al. show that a subset of targets of the growth regulatory transcription factor E2F1 are repressed by a serum-induced PI3K activation, explaining how apoptosis can be suppressed while simultaneously engaging a proliferation program.

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页码：1 / 2

页数：2

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