Olanzapine versus risperidone in the treatment of post-psychotic depression in schizophrenic patients

被引:27
作者
Dollfus, S
Olivier, W
Chabot, B
Déal, C
Perrin, E
机构
[1] Ctr Hosp & Univ, Dept Psychiat, Ctr Esquirol, F-14000 Caen, France
[2] Lilly France, Dept Neurosci, F-91258 Suresnes, France
关键词
schizophrenia; post-psychotic depression; atypical antipsychotics;
D O I
10.1016/j.schres.2005.06.001
中图分类号
R749 [精神病学];
学科分类号
100205 [精神病与精神卫生学];
摘要
Objective: To compare the efficacy of two atypical antipsychotic drugs, olanzapine and risperidone, in schizophrenic patients with post-psychotic depression. Results: A clinically significant decrease of MADRS scores occurred in patients treated with both drugs for 8 weeks. Conclusion: Atypical antipsychotic drugs may be particularly appropriate when treating schizophrenic patients with depression. (c) 2005 Elsevier B.V All rights reserved.
引用
收藏
页码:157 / 159
页数:3
相关论文
共 7 条
[1]
Clinical issues related to depression in schizophrenia: an international survey of psychiatrists [J].
Addington, DD ;
Azorin, JM ;
Falloon, IBH ;
Gerlach, J ;
Hirsch, SR ;
Siris, SG .
ACTA PSYCHIATRICA SCANDINAVICA, 2002, 105 (03) :189-195
[2]
Adjunctive imipramine for a broader group of post-psychotic depressions in schizophrenia [J].
Siris, S ;
Pollack, S ;
Bermanzohn, P ;
Stronger, R .
SCHIZOPHRENIA RESEARCH, 2000, 44 (03) :187-192
[3]
Suicide and schizophrenia [J].
Siris, SG .
JOURNAL OF PSYCHOPHARMACOLOGY, 2001, 15 (02) :127-135
[4]
Depression in schizophrenia: Perspective in the era of "atypical" antipsychotic agents [J].
Siris, SG .
AMERICAN JOURNAL OF PSYCHIATRY, 2000, 157 (09) :1379-1389
[5]
Depressive signs and symptoms in schizophrenia - A prospective blinded trial of olanzapine and haloperidol [J].
Tollefson, GD ;
Sanger, TM ;
Lu, YL ;
Thieme, ME .
ARCHIVES OF GENERAL PSYCHIATRY, 1998, 55 (03) :250-258
[6]
The course of depressive symptoms in predicting relapse in schizophrenia: A double-blind, randomized comparison of olanzapine and risperidone [J].
Tollefson, GD ;
Andersen, SW ;
Tran, PV .
BIOLOGICAL PSYCHIATRY, 1999, 46 (03) :365-373