SCID: the role of adenosine deaminase deficiency

被引：61

作者：

Resta, R

Thompson, LF

机构：

来源：

IMMUNOLOGY TODAY | 1997年 / 18卷 / 08期

关键词：

D O I：

10.1016/S0167-5699(97)01047-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A convincing biochemical explanation for how adenosine deaminase deficiency leads to immunodeficiency has been elusive. This article suggests that aberrant adenosine receptor signaling in the thymus may be important.

引用

页码：371 / 374

页数：4

共 25 条

[1] Metabolic and immunologic consequences of limited adenosine deaminase expression in mice [J].

Blackburn, MR ;

Datta, SK ;

Wakamiya, M ;

Vartabedian, BS ;

Kellems, RE .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (25) :15203-15210

[2] ADENOSINE LEVELS IN THE POSTIMPLANTATION MOUSE UTERUS - QUANTITATION BY HPLC-FLUOROMETRIC DETECTION AND SPATIOTEMPORAL REGULATION BY 5'-NUCLEOTIDASE AND ADENOSINE-DEAMINASE [J].

BLACKBURN, MR ;

XIANG, G ;

AIRHART, MJ ;

SKALKO, RG ;

THOMPSON, LF ;

KNUDSEN, TB .

DEVELOPMENTAL DYNAMICS, 1992, 194 (02) :155-168

[3] Hepatic dysfunction as a complication of adenosine deaminase deficiency [J].

Bollinger, ME ;

ArredondoVega, FX ;

Santisteban, I ;

Schwarz, K ;

Hershfield, MS ;

Lederman, HM .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (21) :1367-1371

[4]

CHECHIK BE, 1981, J IMMUNOL, V126, P1003

[5]

GREENBERG ML, 1989, J BIOL CHEM, V264, P795

[6]

Hershfield MS, 1995, METABOLIC MOL BASES, V2, P1725

[7] BONE-MARROW TRANSPLANTATION ONLY PARTIALLY RESTORES PURINE METABOLITES TO NORMAL IN ADENOSINE DEAMINASE-DEFICIENT PATIENTS [J].

HIRSCHHORN, R ;

ROEGNERMANISCALCO, V ;

KURITSKY, L ;

ROSEN, FS .

JOURNAL OF CLINICAL INVESTIGATION, 1981, 68 (06) :1387-1393

[8]

Jenkinson E J, 1990, Semin Immunol, V2, P51

[9]

Kitakaze M, 1996, BASIC RES CARDIOL, V91, P23

[10]

KIZAKI H, 1990, J BIOL CHEM, V265, P5280

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