A new botulinum toxin type A free of complexing proteins for treatment of cervical dystonia

被引：207

作者：

Benecke, R

Jost, WH

Kanovsky, P

Ruzicka, E

Comes, G

Grafe, S

机构：

[1] Univ Rostock, Dept Neurol, D-18147 Rostock, Germany

[2] Deutsch Klin Diagnost, Dept Neurol, D-6200 Wiesbaden, Germany

[3] Masaryk Univ, Dept Neurol, Brno, Czech Republic

[4] Charles Univ, Dept Neurol, CR-11636 Prague, Czech Republic

[5] Merz Pharmaceut GmbH, Frankfurt, Germany

来源：

NEUROLOGY | 2005年 / 64卷 / 11期

关键词：

D O I：

10.1212/01.WNL.0000163767.99354.C3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A new botulinum toxin type A free of complexing proteins (NT 201) was compared with BOTOX in patients with cervical dystonia by means of a double-blind noninferiority trial. Four hundred sixty-three patients received IM injections of 70 to 300 U of NT 201 or BOTOX and were followed up over 16 weeks. The study clearly shows that NT 201 is at least as effective and safe as BOTOX.

引用

页码：1949 / 1951

页数：3

共 10 条

[1]

Consky ES, 1994, Ther Botulinum Toxin, P211

[2] Botulinum a toxin therapy: Neutralizing and nonneutralizing antibodies-therapeutic consequences [J].