Relationship of Leptin, Resting Metabolic Rate, and Body Composition in PreMenopausal Hispanic and Non-Hispanic White Women

被引:9
作者
Deemer, Sarah E. [1 ]
King, George A. [1 ]
Dorgo, Sandor [1 ]
Vella, Chantal A. [1 ]
Tomaka, Joe W. [2 ]
Thompson, Dixie L. [3 ]
机构
[1] Univ Texas El Paso, Dept Kinesiol, El Paso, TX 79902 USA
[2] Univ Texas El Paso, Dept Publ Hlth, El Paso, TX 79902 USA
[3] Univ Tennessee, Dept Exercise Sport & Leisure Studies, Knoxville, TN USA
基金
美国国家卫生研究院;
关键词
Hormone; Ethnicity; RMR; Human; ENERGY-EXPENDITURE; PLASMA LEPTIN; INSULIN-SENSITIVITY; WEIGHT REGULATION; AFRICAN-AMERICAN; UNITED-STATES; SERUM LEPTIN; OBESE GENE; PROTEIN; OVERWEIGHT;
D O I
10.3109/07435800.2010.496088
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Objective. The purpose was to evaluate the relationships between fasting serum leptin, resting metabolic rate (RMR), and body composition in premenopausal Hispanic and non-Hispanic White (White) women. Methods. Participants were 67 Hispanic and 43 White women who arrived at the laboratory in a fasted state for measurement of RMR by indirect calorimetry, bone mineral content measured by dual-energy X-ray absorptiometry, and body density measured by hydrodensitometry. Serum leptin levels were determined by EIA. Results. Multiple regression analysis revealed that body mass and lean body mass were the best predictors of RMR. Leptin was not a significant predictor of RMR. Conclusion. Further research needs to be done to examine the role of leptin on metabolism, especially in ethnic groups predisposed to development of obesity and related disorders.
引用
收藏
页码:95 / 105
页数:11
相关论文
共 34 条
[1]
Resting metabolic rate in obese, premenopausal black women [J].
Albu, J ;
Shur, M ;
Curi, M ;
Murphy, L ;
Heymsfield, SB ;
PiSunyer, FX .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1997, 66 (03) :531-538
[2]
Free and protein bound leptin are distinct and independently controlled factors in energy regulation [J].
Brabant, G ;
Horn, R ;
von zur Mühlen, A ;
Mayr, B ;
Wurster, U ;
Heidenreich, E ;
Schnabel, D ;
Grüters-Kieslich, A ;
Zimmermann-Belsing, T ;
Feldt-Rasmussen, U .
DIABETOLOGIA, 2000, 43 (04) :438-442
[3]
RECOMBINANT MOUSE OB PROTEIN - EVIDENCE FOR A PERIPHERAL SIGNAL LINKING ADIPOSITY AND CENTRAL NEURAL NETWORKS [J].
CAMPFIELD, LA ;
SMITH, FJ ;
GUISEZ, Y ;
DEVOS, R ;
BURN, P .
SCIENCE, 1995, 269 (5223) :546-549
[4]
Cone RD., 2003, WILLIAMS TXB ENDOCRI, P81
[5]
Mutation screening and identification of a sequence variation in the human OB gene coding region [J].
Considine, RV ;
Considine, EL ;
Williams, CJ ;
Nyce, MR ;
Zhang, P ;
Opentanova, I ;
Ohannesian, JP ;
Kolaczynski, JW ;
Bauer, TL ;
Moore, JH ;
Caro, JF .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 220 (03) :735-739
[6]
LOWER SEDENTARY METABOLIC-RATE IN WOMEN COMPARED WITH MEN [J].
FERRARO, R ;
LILLIOJA, S ;
FONTVIEILLE, AM ;
RISING, R ;
BOGARDUS, C ;
RAVUSSIN, E .
JOURNAL OF CLINICAL INVESTIGATION, 1992, 90 (03) :780-784
[7]
Low plasma leptin concentration and low rates of fat oxidation in weight-stable post-obese subjects [J].
Filozof, CM ;
Murúa, C ;
Sanchez, MP ;
Brailovsky, C ;
Perman, M ;
Gonzalez, CD ;
Ravussin, E .
OBESITY RESEARCH, 2000, 8 (03) :205-210
[8]
Differences in resting metabolic rates of inactive obese African-American and Caucasian women [J].
Forman, JN ;
Miller, WC ;
Szymanski, LM ;
Fernhall, B .
INTERNATIONAL JOURNAL OF OBESITY, 1998, 22 (03) :215-221
[9]
Organ-tissue mass measurement allows modeling of REE and metabolically active tissue mass [J].
Gallagher, D ;
Belmonte, D ;
Deurenberg, P ;
Wang, ZM ;
Krasnow, N ;
Pi-Sunyer, FX ;
Heymsfield, SB .
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 1998, 275 (02) :E249-E258
[10]
WEIGHT-REDUCING EFFECTS OF THE PLASMA-PROTEIN ENCODED BY THE OBESE GENE [J].
HALAAS, JL ;
GAJIWALA, KS ;
MAFFEI, M ;
COHEN, SL ;
CHAIT, BT ;
RABINOWITZ, D ;
LALLONE, RL ;
BURLEY, SK ;
FRIEDMAN, JM .
SCIENCE, 1995, 269 (5223) :543-546