Assemblies: the good, the bad, the ugly

被引：21

作者：

Birney, Ewan ^{[1
]}

机构：

[1] European Bioinformat Inst, European Mol Biol Lab, Hinxton, Cambs, England

来源：

NATURE METHODS | 2011年 / 8卷 / 01期

关键词：

D O I：

10.1038/nmeth0111-59

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The low cost of short-read sequencing has motivated the development of de novo assemblies from only short-read data; impressively, assemblies for large mammalian genomes are now available. However, this is still a developing field, and these de novo assemblies have many artifacts, as do all de novo assemblies.

引用

页码：59 / 60

页数：2

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