Diterpenoids from Azorella yareta and their trichomonicidal activities

被引:45
作者
Loyola, LA [1 ]
Bórquez, J
Morales, G
Araya, J
González, J
Neira, I
Sagua, H
San-Martín, A
机构
[1] Univ Antofagasta, Fac Ciencias Basicas, Dept Quim, Lab Prod Nat, Antofagasta, Chile
[2] Univ Antofagasta, Fac Ciencias Salud, Unidad Parasitol, Antofagasta, Chile
[3] Univ Chile, Fac Ciencias, Dept Quim, Santiago, Chile
关键词
Azorella yareta Hauman; umbelliferae; diterpenoid; mulinane and azorellane derivatives; mulinolic acid; mulin-11,13-dien-20-oic acid; azorellanol; 13; alpha-hydroxyazorellane; beta-hydroxyazorellane; trichomonicidal activity; Trichomona vaginalis;
D O I
10.1016/S0031-9422(00)00380-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Diterpenoids with trichomonicidal activity were isolated from the aerial parts of Azorella yareta Hauman. One was 13 beta -hydroxy-azorellane, together with the known constituents mulinolic acid, mulin-11,13-dien-20-oic acid, azorellanol and 13 alpha -hydroxyazorellane. Their structures were determined by spectroscopic and chemical methods. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:177 / 180
页数:4
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